GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE Basic information
- Product Name:
- GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE
- Synonyms:
-
- GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE
- M871
- TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLU-HIS-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2
- L-Alaninamide, L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-α-glutamyl-L-histidyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-
- WTLNSAGYLLGPEHPPPALALA-NH2
- M871 TFA
- M871, Galanin GAL2 receptor antagonist
- CAS:
- 908844-75-7
- MF:
- C108H163N27O28
- MW:
- 2287.61
- Mol File:
- 908844-75-7.mol
More
Less
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE Chemical Properties
- storage temp.
- Desiccate at -20°C
- solubility
- Soluble to 1 mg/ml in 30% acetonitrile
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 1 mg/ml in water
- Sequence
- H2N-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Glu-His-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2
More
Less
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE Usage And Synthesis
Description
Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists.
Uses
M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM and 420 nM for GalR2 and GalR1, respectively. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain)[1].
storage
Store at -20°C
References
[1] U. E. Sollenberg, et al. M871—A Novel Peptide Antagonist Selectively Recognizing the Galanin Receptor Type 2. Int J Pept Res Ther. 2006;12:2965-2982.
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Nanjing Chemlin Chemical Co., Ltd
- Tel
- 025-83697070
- info@chemlin.com.cn
Creative Peptides
- Tel
- info@creative-peptides.com
Chengdu Youngshe Chemical Co., Ltd.
- Tel
- +86-17380623303
- Caroline@youngshechem.com
Hangzhou Peptidego Biotech Co.,Ltd.
- Tel
- 0571-87213919
- Eric@peptidego.com
More
Less
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE(908844-75-7)Related Product Information
- α-Conotoxin MII
- A-CONOTOXIN AUIB
- H-SER-PHE-LEU-LEU-ARG-NH2
- DABCYL-LYS-HCOV-SARS REPLICASE POLYPROTEIN 1AB (3235-3246)-GLU-EDANS
- PBP10
- leucokinin I
- H-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-NH2
- 11-Dideuterolinoleic acid
- Met-RANTES (human)
- IKKγ NBD Inhibitory Peptide
- RAGE antagonist peptide
- ALPHA-CGRP (8-37) (RAT)
- GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE