4-(2-carbamoyl-pyridin-4-yloxy)aniline Chemical Properties

Boiling point:

462.5±40.0 °C(Predicted)

Density 

1.315±0.06 g/cm3(Predicted)

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

14.79±0.50(Predicted)

form 

Solid

color 

Brown to Dark Brown

Stability:

Light Sensitive

4-(2-carbamoyl-pyridin-4-yloxy)aniline Usage And Synthesis

Uses

4-(4-Aminophenoxy)-2-pyridinecarboxamide is an intermediate in the synthesis of N-Desmethyl Sorafenib (D293290). N-Desmethyl Sorafenib is a metabolite of Sorafenib (S676850) and has anti-proliferative activity in human breast cancer cells.

4-(2-carbamoyl-pyridin-4-yloxy)aniline(284462-80-2)Related Product Information

• Sorafenib Impurity 43
• 2-Pyridinecarboxylic acid, 4-(4-aMinophenoxy)-
• 4-Chloro-pyridine-2-carbonyl chloride
• CPI-203
• N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea
• Sorafenib impurity 24/N-Methyl-4-[4-[[2-[(methylamino)carbonyl]-4-pyridinyl]amino]phenoxy]-2-pyridinecarboxamide
• Sorafenib Impurity 35
• 6-Chloro-N-methylpyridine-2-carboxamide
• 4-CHLORO-N,N-DIMETHYL-PYRIDINE-2-CARBOXAMIDE
• Sorafenib Related Compound B
• 3-(Trifluoromethyl)phenyl isocyanate
• IFLAB-BB F2108-0089
• 4-(2-Aminophenoxy)-N-methylpicolinamide
• 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine
• 4-(4-Aminophenoxy)-N-methylpicolinamide
• 2-Pyridinecarboxamide,N-methyl-(9CI)
• Sorafenib Impurity 6
• Sorafenib IMpurity C