Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea Chemical Properties

Boiling point:

598.2±60.0 °C(Predicted)

Density 

1.39±0.1 g/cm3(Predicted)

pka

11.39±0.70(Predicted)

form 

lumps

Safety Information

Hazard Codes 

T

Risk Statements 

25

Safety Statements 

45

RIDADR 

UN 2811 6.1 / PGIII

HS Code 

29339900

Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea Usage And Synthesis

Chemical Properties

Solid

Uses

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8a,9S)-6′-methoxy-9-cinchonanyl]thiourea is a bifunctional cinchona organocatalyst, which can be used to synthesize:

• Stereoselective diaryl(nitro)butanone via enantioselective Michael addition of nitromethane to chalcones.
• Enantioselective β-amino acids via asymmetric Mannich reaction of malonates with aryl and alkyl imines.
• The synthesis of 3-indolylmethanamines by the reaction of indoles with imines via asymmetric Friedel-Crafts reaction.
• The enantioselective conjugate addition of active methylene compounds to enones to obtain the corresponding addition products.

Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea(852913-16-7)Related Product Information

• N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea
• 1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC)
• 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1R,2R)-2-(diMethylaMino)cyclohexyl]aMino]--Cyclobutene-1,2-dione
• 1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-(-)-2-(dimethylamino)cyclohexyl]thiourea(R,R-TUC)
• 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(diMethylaMino)cyclohexyl]aMino]-Cyclobutene-1,2-dione