1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC) Chemical Properties

Melting point:

87-88°C

alpha 

+42° (c 1.16, CHCl3)

Boiling point:

380.8±52.0 °C(Predicted)

Density 

1.33±0.1 g/cm3(Predicted)

storage temp. 

2-8°C

form 

Powder

pka

11.76±0.70(Predicted)

color 

white

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC) Usage And Synthesis

Reaction

1. Thiourea catalyst used in the enantio and diastereoselective Michael addition of malonates and ketoesters to nitroolefins.
2. Catalyst used in the enantioselective hydrazination of 1,3-dicarbonyl compounds.
3. Catalyst used for the dynamic resolution of azalactones.
4. Catalyst used in Michael-Aldol reaction of 2-mercaptobenzaldehyde with α,β-unsaturated oxazolidinone.
5. Catalyst for enantioselective synthesis of flavanones and chromanones.
6. Catalyst for the asymmetric Neber Reaction.
7. Catalyst for the three component synthesis of 2,6-diazabicyclo[2.2.2]octanones.

1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC)(851477-20-8)Related Product Information

• N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea
• N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea
• N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(9R)-6'-Methoxycinchonan-9-yl]- Thiourea
• 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1R,2R)-2-(diMethylaMino)cyclohexyl]aMino]--Cyclobutene-1,2-dione
• Epi-N-Quinyl-N’-bis(3,5-trifluoromethyl) phenylthiourea
• 1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-(-)-2-(dimethylamino)cyclohexyl]thiourea(R,R-TUC)
• 3-[[3,5-bis(trifluoroMethyl)phenyl]aMino]-4-[[(1S,2S)-2-(diMethylaMino)cyclohexyl]aMino]-Cyclobutene-1,2-dione
• (1S,2S)-N,N'-Dimethyl-1,2-cyclohexanediamine
• (1S,2S)-(+)-N,N-Dimethylcyclohexane-1,2-diamine
• 1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1S,2S)-(+)-2-(dimethylamino)cyclohexyl]thiourea(S,S-TUC)