ClotriMazole IMpurity A Chemical Properties

Melting point:

138-140°C

Boiling point:

475.9±40.0 °C(Predicted)

Density 

1.13±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

pka

6.28±0.30(Predicted)

form 

Solid

color 

White to Off-White

Major Application

pharmaceutical

InChI

1S/C22H17ClN2/c23-21-13-11-20(12-14-21)22(25-16-15-24-17-25,18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-17H

InChIKey

BLNLHAFFGFCSRK-UHFFFAOYSA-N

SMILES

Clc1ccc(cc1)C([n]4cncc4)(c3ccccc3)c2ccccc2

Safety Information

WGK Germany 

WGK 3

Storage Class

13 - Non Combustible Solids

Hazard Classifications

Aquatic Chronic 4

ClotriMazole IMpurity A Usage And Synthesis

Uses

para-Clotrimazole Isomer is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rode nts.

Uses

para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.

ClotriMazole IMpurity A(23593-71-7)Related Product Information

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