Anti-Ring finger protein 125
Anti-Ring finger protein 125 Basic information
- Product Name:
- Anti-Ring finger protein 125
- Synonyms:
-
- Anti-RNF125 antibody produced in rabbit
- Monoclonal Anti-NCOR2 antibody produced in mouse
- Monoclonal Anti-RNF125 antibody produced in mouse
- Anti-Flj20456
- Anti-Ring finger protein 125
- E3 ubiquitin-protein ligase RNF125
- RING finger protein 125
- T-cell RING activation protein 1
- MW:
- 0
- Mol File:
- Mol File
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Anti-Ring finger protein 125 Chemical Properties
- storage temp.
- -20°C
- form
- buffered aqueous glycerol solution
- biological source
- rabbit
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Anti-Ring finger protein 125 Usage And Synthesis
Uses
Useful for the study of enzyme kinetics, screening inhibitors and selectivity profiling.
Biological Activity
RNF125 (ring finger protein 125) acts as a positive regulator in the T-cell receptor-signaling pathway. It stimulates the degradation and suppression of p53. RNF125 plays a major role in lymph node metastasis of colorectal cancer. It stimulates the invasion and metastasis of human gallbladder cancer. In primary human peripheral blood mononuclear cells, RNF125 downregulates HIV-1 (human immunodeficiency virus type 1) replication. Mutations in RNF125 results in a new overgrowth syndrome.