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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  (R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)

(R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)

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(R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE) Basic information

Product Name:
(R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)
Synonyms:
  • 2,6-BIS[(4R)-(+)-ISOPROPYL-2-OXAZOLIN-2-YL]PYRIDINE
  • (+)-2,6-BIS[(4R)-4-(I-PROPYL)-2-OXAZOLIN-2-YL]PYRIDINE
  • 2,6-bis((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine
  • 2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine 99%
  • (+)-2,6-Bis[(4R)-4-(i-propyl)-2-oxazolin-2-yl]pyridine,97%
  • 2,6-Bis[(4R)-isopropyl-2-oxazolin-2-yl]pyridine,99%e.e.
  • (R,R)-2,6-BIS(4-ISOPROPYL-2-OXAZOLIN-2-YL)PYRIDINE
  • (R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)
CAS:
131864-67-0
MF:
C17H23N3O2
MW:
301.38
Product Categories:
  • organic amine
  • BOX series
  • Chiral Catalysts, Ligands, and Reagents
  • Privileged Ligands and Complexes
  • PyBOX
  • Chiral Nitrogen
  • Asymmetric Synthesis
  • Synthetic Organic Chemistry
Mol File:
131864-67-0.mol
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(R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE) Chemical Properties

Melting point:
154-156 °C(lit.)
alpha 
+118° (c 1.0, CH2Cl2)
Boiling point:
457.1±30.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
refractive index 
118 ° (C=1, CH2Cl2)
storage temp. 
Inert atmosphere,Room Temperature
form 
crystal
pka
3.78±0.70(Predicted)
color 
white
optical activity
[α]20/D +118°, c = 0.7 in methylene chloride
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29349990

MSDS

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(R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE) Usage And Synthesis

Reaction

  1. Ligand for enantioselective nitrone cycloaddition to α,β-unsaturated 2-acyl imidazoles.
  2. Highly efficient catalytic enantioselective Mannich reaction of malonates with N-tert-butoxycarbonyl imines.

Chemical Properties

White powder

Uses

C2 symmetric ligand for enantioselective catalysis. Easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals.

(R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)Supplier

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