3-BROMO-4-METHOXYTOLUENE Chemical Properties

Melting point:

15.5 °C(lit.)

Boiling point:

124-125 °C20 mm Hg(lit.)

Density 

1.392 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.565(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

form 

liquid

Specific Gravity

1.41

color 

Clear, dark yellow to brown

CAS DataBase Reference

22002-45-5(CAS DataBase Reference)

EPA Substance Registry System

2-Bromo-4-methylanisole (22002-45-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2909309090

MSDS

• Language:English Provider:SigmaAldrich

3-BROMO-4-METHOXYTOLUENE Usage And Synthesis

Chemical Properties

Clear colourless to light yellow liquid

Uses

2-Bromo-4-methylanisole may be used in the synthesis of:

• 1,6-bis(2-hydroxy-5-methylphenyl)pyridine (H₂mdppy)
• 1,8-dimethoxy-4-methylanthra-quinone
• ethyl 2-(2-methoxy-5-methylphenyl)-2-methyl-4-oxocyclopentanecarboxylate

It may be used as starting material in the multi-step synthesis of sesquiterpene (±)-herbertenolide.

Synthesis Reference(s)

Synthetic Communications, 23, p. 779, 1993 DOI: 10.1080/00397919308009839

General Description

2-Bromo-4-methylanisole can be prepared via bromination of 4-methylanisole using poly(4-vinylpyridinium bromochromate).

3-BROMO-4-METHOXYTOLUENE(22002-45-5)Related Product Information

• 3-Bromo-4-methoxybenzaldehyde
• 3-BROMO-4-METHOXYPHENYLACETONITRILE
• 3-BROMO-4-METHOXYTOLUENE
• 4,4'-Isopropylidenebis[2-(2,6-dibromophenoxy)ethanol]
• Bromoxynil octanoate
• 3-BROMO-4-METHOXYBENZOIC ACID
• Tetrabromobisphenol A bis(dibromopropyl ether)
• 3-BROMO-4-METHOXYPHENYLACETIC ACID
• BROMOXYNIL-METHYL ETHER
• 5-BROMO-2-METHOXYTOLUENE 98+%,5-BROMO-2-METHOXYTOLUENE
• 1-Bromo-3-methoxy-5-methylbenzene3-bromo-5-methoxytoluene,3-BROMO-5-METHOXYTOLUENE
• 2-BROMO-5-METHOXYTOLUENE,2-Bromo-5-methoxytoluene 98%,2-Bromo-5-methoxytoluene (4-bromo-3-methylanisole)
• 5-BROMO-2,4-DIMETHOXYBENZALDEHYDE
• BOC-3,5-DIBROMO-TYR(OBZL)-OH
• 3,5-DIBROMO-4-METHOXYBENZOIC ACID
• EOSIN DIACETATE
• 5-BROMOVERATRALDEHYDE
• 4-BROMO-2-METHOXYTOLUENE