1,1,1-Trifluoro-2,3-epoxypropane Chemical Properties

Boiling point:

38 °C

Density 

1,3 g/cm³

refractive index 

1.2997

Flash point:

-40°C

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

Specific Gravity

1.3068

Water Solubility 

Not miscible with water.

Sensitive 

Moisture Sensitive

BRN 

103730

InChI

InChI=1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2

InChIKey

AQZRARFZZMGLHL-UHFFFAOYSA-N

SMILES

O1CC1C(F)(F)F

CAS DataBase Reference

359-41-1(CAS DataBase Reference)

NIST Chemistry Reference

3,3,3-Trifluoro-1,2-epoxypropane(359-41-1)

Safety Information

Hazard Codes 

F,T

Risk Statements 

11-20/21/22-36/37/38

Safety Statements 

16-26-36-36/37-9

RIDADR 

1993

Hazard Note 

Flammable/Toxic/Keep Cold

HazardClass 

3

PackingGroup 

II

HS Code 

29109000

MSDS

• Language:English Provider:3,3,3-Trifluoro-1,2-epoxypropane
• Language:English Provider:ALFA

1,1,1-Trifluoro-2,3-epoxypropane Usage And Synthesis

Uses

1,2-Epoxy-3,3,3-trifluoropropane is used for the synthesis of trifluorolactic acid. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Synthesis

31g of sodium hydroxide (3.28equiv.: 0.781mol)-water 60ml solution under ice-cooling, 50g bromohydrin form obtained in Example 6 (0.238mol) was added and the internal temperature was raised to 61 oC gas generated was collected outside the reactor, condensed in a trap cooled to -78 oC, 1,1,1-trifluoro-2 ,3-epoxypropane was obtained in 84% yield. This was analyzed by 1H-NMR, 19F-NMR. 19F-NMR: (acetone weight):-86.90ppm (3F, d) 1H-NMR: (acetone weight): 2.90ppm (1H, m) 2.96ppm (1H, d d), 3.40ppm (1H, m)

Synthesis

 To an autoclave (stainless steel, volume:1L) equipped with a mixing tank and a stirrer, C4F9I which compound (1) flow rate 25mL/min, CF2=CF2 (tetrafluoroethylene) which compound (2) flow rate 0.37g/min, (C2F5COO)2 (10 and half hour life temperature: 31°C) which compound (4) flow rate 0.052 mmol/min were supplied, the mixture was prepared by mixing at stirrer. Temperature in the autoclave was 10°C, residence time of the mixture in the autoclave was 10 minutes. The molar ratio (C4F9I/CF2=CF2)of C4F9I and CF2=CF2 in the mixed solution was 41, the amount of (C2F5COO)2 with respect to C4F9I was 0.034 mol%. Only the mixture from the bottom of the autoclave was withdrawn in the absence of gas phase, the mixture was fed to the bottom of tubular reactor (Tankan-shiki, volume: 0.5L). The mixture was not seperated by gas-liquid separation, the mixture was flow towards the outlet from the inlet of the reaction tube in the tube reactor. The temperature of the reaction tube, and a 70°C, the residence time of the mixture in the tubular reactor was set to 20 minutes. The mixture containing a compound (3) C6F13I was obtained.

1,1,1-Trifluoro-2,3-epoxypropane(359-41-1)Related Product Information

• POLY(PERFLUOROPROPYLENE OXIDE)
• Isobutylene oxide
• Propylene oxide
• Hexafluoropropylene oxide
• Epichlorohydrin
• (S)-3,3,3-Trifluoro-1,2-epoxypropane99%
• (S)-(-)-3,3,3-TRIFLUORO-1,2-EPOXYPROPANE
• R-(+)-3,3,3-TRIFLUORO-1,2-EPOXYPROPANE
• (R)-(+)-1,1,1-Trifluoro-2,3-epoxypropane
• 1,1,1-Trifluoro-2,3-epoxypropane