Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  API >  Anesthetic Agents >  Local anesthetics >  Ropivacaine hydrochloride

Ropivacaine hydrochloride

Basic information Safety Supplier Related

Ropivacaine hydrochloride Basic information

Product Name:
Ropivacaine hydrochloride
Synonyms:
  • Ropivacaine hydrochloride
  • (2S)-N-(2,6-dimethylphenyl)-1-propyl-pipecolinamide hydrochloride
  • (2S)-N-(2,6-dimethylphenyl)-1-propyl-piperidine-2-carboxamide hydrochloride
  • (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
  • Ropivacaine hydrochl
  • ROPIVCACAINE HYDROCHLORIDE
  • ROPIVACAINE HCL
  • (S)-ROPIVACAINE HYDROCHLORIDE
CAS:
98717-15-8
MF:
C17H27ClN2O
MW:
310.86
EINECS:
1312995-182-4
Product Categories:
  • Active Pharmaceutical Ingredients
  • Anesthetic (Local)
Mol File:
98717-15-8.mol
More
Less

Ropivacaine hydrochloride Chemical Properties

Melting point:
260-262°
alpha 
D25 -6.6° (c = 2 in water)
storage temp. 
Store at -20°C
form 
Solid
color 
White to off-white
Water Solubility 
≥ 10.1mg/mL in Water
InChI
InChI=1S/C17H26N2O.ClH/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H
InChIKey
NDNSIBYYUOEUSV-UHFFFAOYSA-N
SMILES
N1(CCC)CCCCC1C(NC1=C(C)C=CC=C1C)=O.[H]Cl
CAS DataBase Reference
98717-15-8(CAS DataBase Reference)
More
Less

Ropivacaine hydrochloride Usage And Synthesis

Uses

anesthetic

Uses

2-Piperidinecarboxamide hydrochloride is a useful research chemical compound.

Definition

ChEBI: The anhydrous form of (S)-ropivacaine hydrochloride.

in vivo

Epidural administration of Ropivacaine hydrochloride effectively blocks neuropathic pain (both mechanical allodynia and heat hyperalgesia) without induction of analgesic tolerance and significantly delays the development of neuropathic pain produced by peripheral nerve injury[1].
Ropivacaine hydrochloride inhibits pressure-induced increases in filtration coefficient (Kf) without affecting pulmonary artery pressure (Ppa), pulmonary capillary pressures (Ppc), and zonal characteristics (ZC)[2].
Ropivacaine hydrochloride prevents pressure-induced lung edema and associated hyperpermeability as evidence by maintaining PaO2, lung wet-to-dry ratio and plasma volume in levels similar to sham rats[2].
Ropivacaine hydrochloride inhibits pressure-induced NO production as evidenced by decreased lung nitro-tyrosine content when compared to hypertensive lungs[2].

Animal Model:Adult Sprague-Dawley rats (300–400g)[2]
Dosage:1 μM
Administration:Infusion (added to the perfusate reservoir)
Result:Attenuated pressure-dependent increases in filtration coefficient (Kf).

Ropivacaine hydrochlorideSupplier

Ark Pharm, Inc.
Tel
847-367-3680
Email
sales@arkpharminc.com
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Email
sales@jingyan-chemical.com
LGM Pharma
Tel
1-(800)-881-8210
Email
inquiries@lgmpharma.com
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768836
Email
1791901229@qq.com
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Email
y.liu@mail.biobiopha.com
More
Less

Ropivacaine hydrochloride(98717-15-8)Related Product Information