TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Chemical Properties

Melting point:

125-131 °C

Boiling point:

140 °C(Press: 2 Torr)

Density 

1.509±0.06 g/cm3(Predicted)

refractive index 

1.4556 (589.3 nm 25℃)

storage temp. 

2-8°C

pka

pK1:3.79 ;pK2:5.61 (25°C)

BRN 

3198993

InChIKey

SUSAGCZZQKACKE-QWWZWVQMSA-N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

RTECS 

GU1680000

HS Code 

2917200090

MSDS

• Language:English Provider:SigmaAldrich

TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Usage And Synthesis

General Description

The interaction of the carboxyl groups in the fragmentation of the molecular ions of cis-cyclobutane-1,2-dicarboxylic acid helps to distinguish it from trans-cyclobutane-1,2-dicarboxylic acid.

Purification Methods

Crystallise the acid from *C6H6 or *C6H6/EtOAc. The diphenacyl ester has m 98o (from EtOH) and the p-bromodiphenacyl ester has m 158o (from EtOH). The cis-acid isomerizes to the trans-acid on heating in conc HCl at 190o. [Reed J Chem Soc 685 1951, Fison et al. J Am Chem Soc 51 1536 1929, Fison et al. J Am Chem Soc 56 1774 1934, pK: Bode Chem Ber 67 332 1934, Beilstein 9 IV 2788.]

TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID(1124-13-6)Related Product Information

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