TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID

Uses

Product Name: TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
CAS No.: 1124-13-6
Chemical Name: TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
Synonyms: TRANS-1,2-CYCLOBUTANEDICARBOXYLIC ACID;1,2-Cyclobutanedicarboxylic acid, trans-;(1R,2R)-Cyclobutane-1,2-dicarboxylic acid;usafst-3;USAF st-3;NSC 527264;RARECHEM AL BO 2332;SPECS AB-131/40227215;trans-Cyclobutane-1, 2-DCA;1,2-Cyclobutanedicarboxylic acid
CBNumber: CB3396108
Molecular Formula: C6H8O4
Formula Weight: 144.13
MOL File: 1124-13-6.mol

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TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Property

Melting point:: 125-131 °C
Boiling point:: 140 °C(Press: 2 Torr)
Density: 1.509±0.06 g/cm3(Predicted)
refractive index: 1.4556 (589.3 nm 25℃)
storage temp.: 2-8°C
form: solid
pka: pK1:3.79 ;pK2:5.61 (25°C)
Appearance: Light yellow to yellow Solid
BRN: 3198993
InChI: InChI=1/C6H8O4/c7-5(8)3-1-2-4(3)6(9)10/h3-4H,1-2H2,(H,7,8)(H,9,10)/t3-,4-/s3
InChIKey: SUSAGCZZQKACKE-QWWZWVQMSA-N
SMILES: [C@@H]1(C(O)=O)CC[C@H]1C(O)=O |&1:0,6,r|

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
RTECS: GU1680000
HS Code: 2917200090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 28684
Product name: trans-Cyclobutane-1,2-dicarboxylic acid
Purity: ≥97.0% (T)
Packaging: 1g
Price: $89
Updated: 2025/07/31

Sigma-Aldrich

Product number: 28684
Product name: trans-Cyclobutane-1,2-dicarboxylic acid
Purity: ≥97.0% (T)
Packaging: 5g
Price: $425
Updated: 2025/07/31

TRC

Product number: C989478
Product name: trans-Cyclobutane-1,2-dicarboxylic acid
Packaging: 1g
Price: $265
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC142698
Product name: trans-Cyclobutane-1,2-dicarboxylic acid
Packaging: 50mg
Price: $59
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2221-1-E1
Product name: trans-Cyclobutane-1,2-dicarboxylic acid
Packaging: 250mg
Price: $95
Updated: 2021/12/16

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TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

trans-1,2-cyclosuccinic acid can be used as a pharmaceutical synthesis intermediate.

Uses

The interaction of the carboxyl groups in the fragmentation of the molecular ions of cis-cyclobutane-1,2-dicarboxylic acid helps to distinguish it from trans-cyclobutane-1,2-dicarboxylic acid.

General Description

The interaction of the carboxyl groups in the fragmentation of the molecular ions of cis-cyclobutane-1,2-dicarboxylic acid helps to distinguish it from trans-cyclobutane-1,2-dicarboxylic acid.

Purification Methods

Crystallise the acid from *C6H6 or *C6H6/EtOAc. The diphenacyl ester has m 98o (from EtOH) and the p-bromodiphenacyl ester has m 158o (from EtOH). The cis-acid isomerizes to the trans-acid on heating in conc HCl at 190o. [Reed J Chem Soc 685 1951, Fison et al. J Am Chem Soc 51 1536 1929, Fison et al. J Am Chem Soc 56 1774 1934, pK: Bode Chem Ber 67 332 1934, Beilstein 9 IV 2788.]

TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Suppliers

Canada 1 China 110 Germany 4 India 8 Japan 1 Switzerland 2 The Netherlands 1 United Kingdom 4 United States 10 Global 141

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Suzhou Junye Biopharmaceutical Technology Co., Ltd

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Bide Pharmatech Ltd.

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View Lastest Price from TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: trans-1,2-cyclobutanedicarboxylic acid 1124-13-6
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-17

Shaanxi Dideu New Materials Co. Ltd

Product: Trans-cyclobutane-1,2-dicarboxylic acid 1124-13-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KG
Release date: 2024-11-10

Longyan Tianhua Biological Technology Co., Ltd

Product: TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID 1124-13-6
Price: US $15.00/Kg/Bag
Min. Order: 25Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-11-13

1124-13-6, TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACIDRelated Search:

trans-1,2-Cyclopentanediol TRANS-1,4-CYCLOHEXANE DIISOCYANATE TRANS-CYCLOBUTANE-1,2-DICARBONITRILE trans-1,2-Cyclohexanedicarboxylic acid trans-1,4-Diaminocyclohexane trans-1,4-Cyclohexanedicarboxybic acid (E)-1,4-Dibromobut-2-ene TRANS-1,4-CYCLOHEXANEDIOL (+/-)-trans-1,2-Diaminocyclohexane DIMETHYL TRANS-1,2-CYCLOPROPANEDICARBOXYLATE 1,3-Cyclopentanediamine,(1R,3R)-rel-(9CI) DIMETHYL TRANS-1,4-CYCLOHEXANEDICARBOXYLATE (+/-)-TRANS-1,2-CYCLOPENTANEDIOL trans-Cyclobutane-1,3-dicarboxylic acid 1,2,3,4-Cyclobutanetetracarboxylic Dianhydride 1,2,3,4-CYCLOBUTANETETRACARBOXYLIC ACID TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER

SPECS AB-131/40227215

RARECHEM AL BO 2332

TRANS-1,2-CYCLOBUTANEDICARBOXYLIC ACID

TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID

(e)-2-cyclobutanedicarboxylicacid

1,2-Cyclobutanedicarboxylic acid

1,2-Cyclobutanedicarboxylic acid, (E)-

1,2-Cyclobutanedicarboxylic acid, trans-

USAF st-3

usafst-3

rel-1α*,2β*-Cyclobutanedicarboxylic acid

(1R,2R)-rel-1,2-Cyclobutanedicarboxylic acid

trans-Cyclobutane-1,2-dicarboxylic acid (racemic)

(1R,2R)(1S,2S)-Cyclobutane-1,2-dicarboxylic acid

trans-Cyclobutane-1,2-dicarboxylic acid

NSC 527264

(1R,2R)-Cyclobutane-1,2-dicarboxylic acid

1,2-Cyclobutanedicarboxylic acid, (1R,2R)-rel-

TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID ISO 9001：2015 REACH

(1S,2S)-cyclobutane-1,2-dicarboxylic acid

trans-Cyclobutane-1, 2-DCA

TRANS-CYCLOBUTANE-1,2-DICARBOXALIC ACID

trans-Cyclobutane-1,2-dicarboxylic acid

(1R,2R)-rel-1,2-Cyclobutanedicarboxylic acid - [C13294]

1124-13-6

Carbonyl Compounds

Carboxylic Acids

Building Blocks

Organic Building Blocks

C6

Carbonyl Compounds

Carboxylic Acids

C6