(+/-)-trans-1,2-Diaminocyclohexane Chemical Properties

Melting point:

14-15 °C(lit.)

Boiling point:

79-81 °C15 mm Hg(lit.)

Density 

0.951 g/mL at 25 °C(lit.)

vapor pressure 

0.4 mm Hg ( 20 °C)

refractive index 

n20/D 1.489(lit.)

Flash point:

156 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Liquid

pka

9.94(at 20℃)

color 

Clear colorless to light yellow

Water Solubility 

Soluble

Sensitive 

Air Sensitive

BRN 

506142

InChIKey

SSJXIUAHEKJCMH-WDSKDSINSA-N

CAS DataBase Reference

1121-22-8(CAS DataBase Reference)

NIST Chemistry Reference

trans-1,2-Cyclohexanediamine(1121-22-8)

EPA Substance Registry System

1,2-Cyclohexanediamine, (1R,2R)-rel- (1121-22-8)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2735 8/PG 2

WGK Germany 

3

F 

10-34

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29213000

MSDS

• Language:English Provider:(+/-)-trans-1,2-Cyclohexanediamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

(+/-)-trans-1,2-Diaminocyclohexane Usage And Synthesis

Chemical Properties

clear colorless to light yellow liquid

Uses

(^+)-trans-1,2-Diaminocyclohexane is employed in the synthesis of macrocyclic [3+3] hexa Schiff base. It also plays an important role in the preparation of multidentate ligands, chiral auxiliaries and chiral stationary phases. Further, it is used to prepare [2+2] macrocyclization by reacting with aliphatic dialdehydes. In addition to this, it acts as a chiral ligand, which finds application in asymmetric catalysis.

Uses

(±)-trans-1,2-Diaminocyclohexane was used in the synthesis of macrocyclic [3+3] hexa Schiff base. It was also employed in the synthesis of multidentate ligands, chiral auxiliaries and chiral stationary phases.

General Description

(±)-trans-1,2-Diaminocyclohexane was condensed with aliphatic dialdehydes to form [3+3] or [2+2] macrocyclization products.

Purification Methods

Purify and store the diamine as for the cis-isomer above as it is a strong base and becomes yellow on storage. [Beilstein 13 IV 1.]

(+/-)-trans-1,2-Diaminocyclohexane(1121-22-8)Related Product Information

• 1,2-Cyclohexanedione
• Hexamethylenediamine
• 1,2-Cyclohexanediol
• TRANS-1,4-DIAMINOCYCLOHEXANE
• trans,trans-2,4-Undecadienal
• TRANS-1,4-CYCLOHEXANEDIOL
• trans-1,2-Cyclopentanediol
• (E)-1,4-Dibromobut-2-ene
• TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
• trans-1,4-Cyclohexanedicarboxybic acid
• TRANS-1,2-CYCLOHEXANEDIOL
• rich_d_transallethrin
• (1R)-TRANS-1,2-DIAMINOCYCLOHEXANE,(1R)-(-)-TRANS-1,2-DIAMINOCYCLOHEXANE
• Enadoline
• (1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL)
• (1S,2S)-(+)-[1,2-CYCLOHEXANEDIAMINO-N N'-BIS(3,5-DI-T-BUTYLSALICYLIDENE)]ALUMINUM (III) CHLORIDE
• (S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO-COBALT(II)
• (1S)-TRANS-1,2-DIAMINOCYCLOHEXANE D-TARTRATE