Dimethylaminopropionitrile Chemical Properties

Melting point:

−43 °C(lit.)

Boiling point:

171 °C750 mm Hg(lit.)

Density 

0.87 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.426(lit.)

Flash point:

145 °F

storage temp. 

2-8°C

form 

Liquid

pka

8.17±0.28(Predicted)

color 

Clear colorless to yellow

PH

10.8 (100g/l, H2O, 20℃)

explosive limit

1.6-11.4%(V)

Water Solubility 

0.5 g/L (20 ºC)

BRN 

773779

CAS DataBase Reference

1738-25-6(CAS DataBase Reference)

NIST Chemistry Reference

Propanenitrile, 3-(dimethylamino)-(1738-25-6)

EPA Substance Registry System

Dimethylaminopropionitrile (1738-25-6)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36-36/38-21

Safety Statements 

26-36/37-24/25

RIDADR 

2927

WGK Germany 

1

RTECS 

UG1575000

F 

8

TSCA 

Yes

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29269095

Hazardous Substances Data

1738-25-6(Hazardous Substances Data)

MSDS

• Language:English Provider:Dimethylaminopropionitrile
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Dimethylaminopropionitrile Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

3-(Dimethylamino)propionitrile has been used:

• to initiate the organic polymerization during the synthesis of class I hybrid poly(N-isopropylacrylamide)/silica hydrogels
• in preparation of cysteine modifying agents based on the solvatochromic fluorophore 4-N,N-dimethylamino-1,8-naphthalimide (4-DMN)

Uses

3- Dimethylaminopropionitrile is used as a solvent, dielectric fluid, and an intermediate.

Production Methods

3-Dimethylaminopropionitrile is derived from heating barium ethyl sulfate and KCN with subsequent distillation.

General Description

Colorless liquid. Mp: -44.3°C; bp: 171-172°C. Density 0.87 g cm-3 at 20°C). Water-soluble. Used in the manufacture of polyurethane foam. Excessive exposure leads to urologic and neurologic disorders.

Reactivity Profile

Dimethylaminopropionitrile is combustible but non-flammable (flash point > 140°F), reacts with oxidizing agents (Hazardous Chemicals Desk Reference, p. 426 (1987)). Reacts violently with LIAlH4, a strong reducing agent. Emits toxic oxides of nitrogen and cyanide fumes when heated to decomposition.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and skin contact. A skin and eye irritant. Flammable liquid when exposed to heat, flame, or oxidizers; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of NOx and CN-. See also NITRILES.

Dimethylaminopropionitrile(1738-25-6)Related Product Information

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