5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE Chemical Properties

Melting point:

153-154

Boiling point:

433.3±45.0 °C(Predicted)

Density 

1.49±0.1 g/cm3(Predicted)

pka

-1.59±0.50(Predicted)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

22

Hazard Note 

Irritant

HS Code 

2933199090

5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE Usage And Synthesis

Uses

5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile is an intermediate in the synthesis of Binucleine 2 (B387153). Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. Highly isoform-specific inhibitor of Drosophila Aurora B kinase.

5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE(175135-53-2)Related Product Information

• 5-AMINO-1-PHENYLPYRAZOLE
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• 5-AMINO-1-(3-CHLOROPHENYL)-1H-PYRAZOLE-&
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• 3-Amino-4-pyrazolecarbonitrile
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• 4-METHYL-1H-PYRAZOL-3-AMINE
• 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE
• 4-METHYLPYRAZOLE HYDROCHLORIDE
• 1-PHENYL-1H-PYRAZOLE-4-CARBONITRILE
• 5-AMINO-4-CYANO-1-(4-FLUOROPHENYL)PYRAZOLE