ChemicalBook > CAS DataBase List > 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE

5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE

Product Name
5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE
CAS No.
175135-53-2
Chemical Name
5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE
Synonyms
5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE;5-AMINO-4-CYANO-1-(3-CHLORO-4-FLUOROPHENYL)PYRAZOLE;5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole97%;5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 97%;5-amino-1-(3-chloro-4-fluorophenyl)-4-pyrazolecarbonitrile;5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE;1H-Pyrazole-4-carbonitrile, 5-amino-1-(3-chloro-4-fluorophenyl)-;5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile
CBNumber
CB3428847
Molecular Formula
C10H6ClFN4
Formula Weight
236.63
MOL File
175135-53-2.mol
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5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE Property

Melting point:
153-154
Boiling point:
433.3±45.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
form 
solid
pka
-1.59±0.50(Predicted)
InChI
1S/C10H6ClFN4/c11-8-3-7(1-2-9(8)12)16-10(14)6(4-13)5-15-16/h1-3,5H,14H2
InChIKey
CQCMIVONXGCSME-UHFFFAOYSA-N
SMILES
Nc1c(cnn1-c2ccc(F)c(Cl)c2)C#N
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
WGK Germany 
WGK 3
Hazard Note 
Irritant
HS Code 
2933199090
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
JRD0283
Product name
5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile
Purity
Aldrich
Packaging
1g
Price
$693
Updated
2025/07/31
TRC
Product number
A603443
Product name
5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile
Packaging
250mg
Price
$2675
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COR0003258
Product name
5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Purity
95.00%
Packaging
5G
Price
$4244.63
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COR0003258
Product name
5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Purity
95.00%
Packaging
10G
Price
$7882.88
Updated
2021/12/16
AK Scientific
Product number
1578CH
Product name
5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile
Packaging
1g
Price
$756
Updated
2021/12/16
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5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE Chemical Properties,Usage,Production

Uses

5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-4-carbonitrile is an intermediate in the synthesis of Binucleine 2 (B387153). Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. Highly isoform-specific inhibitor of Drosophila Aurora B kinase.

5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE Suppliers

SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
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Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
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58
MQ (shanghai) Pharmaceuticals Co., Ltd.
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13761635123
Fax
1014988033@qq
Email
sales@linyuepharm.com
Country
China
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4933
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Bide Pharmatech Ltd.
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400-1647117 13681763483
Email
product02@bidepharm.com
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China
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59936
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Yantai Shengkailun Chemical Technology Co., Ltd.
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13356901049
Email
mark@sklnchem.cn
Country
China
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9939
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
400-6206333 13167063860
Email
anhua.mao@aladdin-e.com
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China
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48049
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Merck KGaA
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21-20338288
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ordercn@merckgroup.com
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China
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Alchem Pharmtech,Inc.
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8485655694
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sales@alchempharmtech.com
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United States
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63687
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Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
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58

175135-53-2, 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLERelated Search:


  • 5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole 97%
  • 5-AMINO-4-CYANO-1-(3-CHLORO-4-FLUOROPHENYL)PYRAZOLE
  • 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
  • 5-AMINO-1-(3-CHLORO-4-FLUOROPHENYL)-4-CYANOPYRAZOLE
  • 5-Amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole97%
  • 5-amino-1-(3-chloro-4-fluorophenyl)-4-pyrazolecarbonitrile
  • 1H-Pyrazole-4-carbonitrile, 5-amino-1-(3-chloro-4-fluorophenyl)-
  • 5-Amino-1-(3-chloro-4-fluorophenyl)-1<i>H</i>-pyrazole-4-carbonitrile
  • 175135-53-2
  • C10H6ClFN4