1-Methyl-1H-pyrazol-5-ylamine

Product Name: 1-Methyl-1H-pyrazol-5-ylamine
CAS No.: 1192-21-8
Chemical Name: 1-Methyl-1H-pyrazol-5-ylamine
Synonyms: 1-METHYL-1H-PYRAZOL-5-AMINE;2-METHYLPYRAZOL-3-AMINE;-5-amine;NSC 76510;AKOS B024266;AKOS PAO-0256;BUTTPARK 18\09-58;ART-CHEM-BB B024266;1-METHYL-5-AMINOPYRAZOLE;5-AMINO-1-METHYLPYRAZOLE
CBNumber: CB3212622
Molecular Formula: C4H7N3
Formula Weight: 97.12
MOL File: 1192-21-8.mol

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1-Methyl-1H-pyrazol-5-ylamine Property

Melting point:: 73 °C
Boiling point:: 95-96°C (0.5 mmHg)
Density: 1.22±0.1 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
pka: 4.16±0.10(Predicted)
color: Dark Red to Orange to Brown
InChI: InChI=1S/C4H7N3/c1-7-4(5)2-3-6-7/h2-3H,5H2,1H3
InChIKey: JESRNIJXVIFVOV-UHFFFAOYSA-N
SMILES: N1(C)C(N)=CC=N1
CAS DataBase Reference: 1192-21-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-36/37/38-22
Safety Statements: 26-36/37/39
RIDADR: 2811
HazardClass: IRRITANT
HS Code: 29331990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A3303
Product name: 5-Amino-1-methylpyrazole
Packaging: 5G
Price: $59
Updated: 2025/07/31

TCI Chemical

Product number: A3303
Product name: 5-Amino-1-methylpyrazole
Packaging: 25G
Price: $234
Updated: 2025/07/31

TRC

Product number: A617475
Product name: 5-Amino-1-methylpyrazole
Packaging: 25g
Price: $180
Updated: 2021/12/16

Usbiological

Product number: A1379-02
Product name: 5-Amino-1-methylpyrazole
Packaging: 2.5g
Price: $340
Updated: 2021/12/16

TRC

Product number: A617475
Product name: 5-Amino-1-methylpyrazole
Packaging: 250g
Price: $835
Updated: 2021/12/16

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1-Methyl-1H-pyrazol-5-ylamine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

An interesting synthetic intermediate

Synthesis

60838-50-8

60-34-4

1192-21-8

General procedure for the synthesis of 1-methyl-5-aminopyrazole (9) from 3-methoxyacrylonitrile (1a) and methylhydrazine (2b): methylhydrazine (2b) (0.25 mL, 4.7 mmol) and 3-methoxyacrylonitrile (1a) (0.20 mL, 2.4 mmol) were dissolved in toluene/acetic acid (4:1 v/v; 5 mL) solvent mixture. The reaction mixture was placed in a sealed pressure rated Pyrex tube (10 mL) and microwave irradiated for 1 h at 120 °C using a CEM Discover microwave synthesizer set at an initial power of 100 W. The reaction was carried out using a CEM Discover microwave synthesizer. After completion of the reaction, the reaction mixture was cooled in a stream of compressed air. Subsequently, the reaction mixture was neutralized with saturated aqueous NaHCO3 solution and extracted with EtOAc (3 × 20 mL). The organic layers were combined, washed sequentially with water and brine, dried over MgSO4, and the solvent was evaporated in vacuum to afford 1-methyl-5-aminopyrazole (0.22 g, 97%) as a light brown solid with a melting point of 71-73 °C (literature value: 71-72 °C). The product was confirmed by high-resolution mass spectrometry (measured value: 97.0640, C4H7N3 [M] theoretical value: 97.0637).1H NMR (400 MHz; DMSO-d6) δ 7.60 (1H, d, J = 2.0 Hz, H-3), 5.15 (1H, d, J = 2.0 Hz, H-4), 3.85 (2H, br s, with D2O exchange, NH2), 3.50 (3H, s, Me); 13C NMR (126 MHz; DMSO-d6) δ 145.6 (C), 138.5 (CH), 90.8 (CH), 34.0 (Me); LRMS (APcI) m/z (relative intensity) 97 (M+, 100).

References

[1] Tetrahedron, 2013, vol. 69, # 39, p. 8429 - 8438

1-Methyl-1H-pyrazol-5-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methyl-1H-pyrazol-5-ylamine Suppliers

Americas 1 Belgium 1 Canada 2 CHINA 210 Europe 1 France 1 Germany 6 India 9 Japan 2 Russia 1 Switzerland 1 United Kingdom 19 United States 41 Global 295

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View Lastest Price from 1-Methyl-1H-pyrazol-5-ylamine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Methyl-1H-pyrazol-5-ylamine 1192-21-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Methyl-1H-pyrazol-5-ylamine 1192-21-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 1-Methyl-1H-pyrazol-5-ylamine 1192-21-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-31

1192-21-8, 1-Methyl-1H-pyrazol-5-ylamineRelated Search:

5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 5-AMINO-4-CYANO-3-CYANOMETHYL-1-PHENYLPYRAZOLE 5-AMINO-1-PHENYLPYRAZOLE-4-CARBONITRILE 5-AMINO-4-CYANO-1-(2-HYDROXYETHYL)PYRAZOLE 1,3-Dimethyl-1H-pyrazol-5-amine 1,4,6-Trimethyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine ,97% 5-Amino-3-methyl-1-phenylpyrazole 5-AMINO-1-PHENYLPYRAZOLE 5-AMINO-4-CARBETHOXY-1-PHENYLPYRAZOLE ETHYL 5-AMINO-1-METHYLPYRAZOLE-4-CARBOXYLATE 5-AMINO-1-PHENYLPYRAZOLE-4-CARBOXAMIDE 5-AMINO-3-METHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 1-METHYL-1H-PYRAZOL-4-YLAMINE 1-METHYL-1H-PYRAZOL-3-YLAMINE 3-Amino-5-methylpyrazole 6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-amine 1-(3'-Sulfo)phenyl-3-methyl-5-aminopyrazole 4,6-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE

1-Methyl-1H-pyrazol-5-ylamine ,97%

1-Methyl-5-amino-1H-pyrazole

5-Amino-1-methyl-1H-pyrazole 97%

1-Methyl-1H-pyrazol-5-amine, 2-Methyl-2H-pyrazol-3-amine

NSC 76510

1-Methylpyrazol-5-ylaMine

2-Methyl-3-aMino-pyrazole

5-Amino-1-methylpyrazole, >=97%

1H-Pyrazol-5-amine, 1-methyl-

1-METHYL-1H-PYRAZOL-5-AMINE

1-METHYL-1H-PYRAZOL-5-YLAMINE

1-METHYL-5-AMINOPYRAZOLE

BUTTPARK 18\09-58

ART-CHEM-BB B024266

AKOS B024266

AKOS PAO-0256

5-AMINO-1-METHYLPYRAZOLE

5-AMINO-1-METHYL-1H-PYRAZOLE

2-METHYL-2 H-PYRAZOL-3-YLAMINE

2-METHYLPYRAZOL-3-AMINE

5-amino-6-hydroxy-1H-pyrimidine-2,4-dione

5-Amino-1-methylpyrazole 97%

1-METHYL-1H-PYRAZOLE-5-YL AMINE

-5-amine

1192-21-8

C4H7N3

Nucleotides and Nucleosides

Heterocyclic

Nucleotide

Amines

Azoles

blocks

Pyrazole series

Pyrazole