3-Amino-5-methylpyrazole
- Product Name
- 3-Amino-5-methylpyrazole
- CAS No.
- 31230-17-8
- Chemical Name
- 3-Amino-5-methylpyrazole
- Synonyms
- 5-Methyl-1H-pyrazol-3-amine;3-METHYL-1H-PYRAZOL-5-AMINE;3,5-AMP;3,1-AMP;AKOS B016021;3-Amino-5-methyL;AKOS BBS-00004647;BUTTPARK 48\04-98;TIMTEC-BB SBB004375;ART-CHEM-BB B016021
- CBNumber
- CB9174450
- Molecular Formula
- C4H7N3
- Formula Weight
- 97.12
- MOL File
- 31230-17-8.mol
3-Amino-5-methylpyrazole Property
- Melting point:
- 45-47 °C (lit.)
- Boiling point:
- 213 °C/14 mmHg (lit.)
- Density
- 1.0548 (rough estimate)
- refractive index
- 1.5200 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in Dichloromethane and Methanol.
- pka
- 15.84±0.10(Predicted)
- form
- Solid
- color
- Light yellow to orange
- Sensitive
- Air Sensitive
- BRN
- 1904
- Stability:
- Light Sensitive
- InChIKey
- FYTLHYRDGXRYEY-UHFFFAOYSA-N
- CAS DataBase Reference
- 31230-17-8(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Pyrazol-3-amine, 5-methyl- (31230-17-8)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29331990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS004036
- Product name
- 3-Methyl-1<I>H</I>-pyrazol-5-amine
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 250 mg
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- 340200
- Product name
- 3-Amino-5-methylpyrazole
- Purity
- 97%
- Packaging
- 25g
- Price
- $52.6
- Updated
- 2023/06/20
- Product number
- 340200
- Product name
- 3-Amino-5-methylpyrazole
- Purity
- 97%
- Packaging
- 100g
- Price
- $200
- Updated
- 2023/06/20
- Product number
- A1133
- Product name
- 3-Amino-5-methylpyrazole
- Purity
- >96.0%(GC)
- Packaging
- 25g
- Price
- $142
- Updated
- 2025/07/31
- Product number
- A1379-02A
- Product name
- 5-Amino-3-methylpyrazole
- Packaging
- 5g
- Price
- $319
- Updated
- 2021/12/16
3-Amino-5-methylpyrazole Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powde
Uses
3-Amino-5-methyl-1H-pyrazole was employed as beta-sheet template to investigate its interaction with ferrocenoyl-dipeptides. It is also used in the synthesis of 4-aryl-3,7,7-trimethyl-2,4,6,7,8,9-hexahydropyrazolo[3,4-b]quinolin-5-ones. It can react with 4-Ethoxymethylene-2-phenyl-4H-oxazol-5-one to get N-(2-Methyl-7-oxo-4,7-dihydro-pyrazolo[1,5-a]pyrimidin-6-yl)-benzamide.
Uses
3-Amino-5-methylpyrazole was employed as beta-sheet template to investigate its interaction with ferrocenoyl-dipeptides. It was also used in the synthesis of 4-aryl-3,7,7-trimethyl-2,4,6,7,8,9-hexahydropyrazolo[3,4-b]quinolin-5-ones.
Definition
ChEBI: 5-Methyl-3-pyrazolamine is a heterocyclic compound and a dicarboximide.
General Description
Complexation of the amino- and carboxyl-protected tripeptide with 3-amino-5-methylpyrazole was studied by low-temperature NMR experiments in a freonic solvent.
Synthesis
1118-61-2
31230-17-8
General procedure for the synthesis of 3-amino-5-methyl-1H-pyrazole from 3-aminobut-2-enenenitrile: 10 g of 3-aminobut-2-enenitrile and 5 L of ethanol were added to a 10 L reaction flask and stirred until completely dissolved. Subsequently, 2500 g of 80% hydrazine hydrate was added. After stirring at room temperature for 10-20 minutes, the reaction was slowly heated to reflux, keeping the reaction temperature between 85-95 °C. Note: A large amount of gas is generated during the reaction. When the reaction has been carried out for 1.5-2.5 hours, confirm the complete reaction of the feedstock by TLC monitoring. Upon completion of the reaction, the reaction solution is concentrated under reduced pressure at 50-60°C to 20-30% of the original volume. Finally, a light yellow liquid (converted to a light yellow solid after cooling) was obtained by oil pump distillation in a yield of 2230 g with 94.2% yield. The purity of 3-amino-5-methyl-1H-pyrazole was higher than 98% and the content of single impurity was lower than 0.5% by GC and HPLC analysis.
References
[1] Patent: CN108341782, 2018, A. Location in patent: Paragraph 0018; 0019; 0021; 0022
[2] Patent: CN104844567, 2017, B. Location in patent: Paragraph 0031; 0034; 0039; 0044
3-Amino-5-methylpyrazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Amino-5-methylpyrazole manufacturers
- Product
- 3-Amino-5-methylpyrazole 31230-17-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-22
- Product
- 3-Amino-5-methylpyrazole 31230-17-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 20TON
- Release date
- 2024-12-11
- Product
- 3-Amino-5-methylpyrazole 31230-17-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2024-01-02