NPPB Chemical Properties

Melting point:

178-180℃

Boiling point:

523.5±50.0 °C(Predicted)

Density 

1.323±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

ethanol: 3 mg/mL

form 

Yellow solid

pka

2.27±0.22(Predicted)

color 

Light yellow to yellow

InChI

1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)

InChIKey

WBSMIPAMAXNXFS-UHFFFAOYSA-N

SMILES

OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O

Safety Information

WGK Germany 

3

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich

NPPB Usage And Synthesis

Uses

NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.

Uses

Biochemical probe primarily as a Cl- channel blocker.

Definition

ChEBI: 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a nitrobenzoic acid.

Biological Activity

Very potent chloride channel blocker.

Biochem/physiol Actions

Potent chloride channel blocker.

storage

Store at RT

NPPB(107254-86-4)Related Product Information

• 4-Methoxybenzoic acid
• CHLOROTOXIN
• 2-Chloro-4-nitrotoluene
• Benzoic acid
• 2-Nitrobenzoic acid
• Fipronil
• N-Phenylanthranilic acid
• Clopamide
• 2,5-diaminobenzoic acid
• 2-amino-5-nitro-benzaldehyde
• RARECHEM AL BI 1183
• 2-Amino-5-nitrobenzoic acid
• RARECHEM AL BE 1183
• NPPB
• 2-amino-5-nitrobenzyl alcohol
• RARECHEM AL BF 1183