NPPB Chemical Properties

Melting point:

178-180℃

Boiling point:

523.5±50.0 °C(Predicted)

Density 

1.323±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

ethanol: 3 mg/mL

form 

Yellow solid

pka

2.27±0.22(Predicted)

color 

Light yellow to yellow

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

NPPB Usage And Synthesis

Uses

NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.

Uses

Biochemical probe primarily as a Cl- channel blocker.

Definition

ChEBI: 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a nitrobenzoic acid.

Biological Activity

Very potent chloride channel blocker.

Biochem/physiol Actions

Potent chloride channel blocker.

storage

Store at RT

NPPB(107254-86-4)Related Product Information

• 2-Chloro-4-nitrotoluene
• Benzoic acid
• 2-Nitrobenzoic acid
• 4-Methoxybenzoic acid
• Fipronil
• N-Phenylanthranilic acid
• CHLOROTOXIN
• Clopamide
• 2,5-diaminobenzoic acid
• 2-amino-5-nitro-benzaldehyde
• RARECHEM AL BI 1183
• 2-Amino-5-nitrobenzoic acid
• RARECHEM AL BE 1183
• NPPB
• 2-amino-5-nitrobenzyl alcohol
• RARECHEM AL BF 1183