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NPPB

Product Name
NPPB
CAS No.
107254-86-4
Chemical Name
NPPB
Synonyms
NPPB;C13705;Compound 144;Recombinant Human NPPB Protein, His Tag;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE;5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID;5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID;3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid;5-Nitro-2-(3-phenylpropylamino)benzoic acid,NPPB;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%
CBNumber
CB3450426
Molecular Formula
C16H16N2O4
Formula Weight
300.31
MOL File
107254-86-4.mol
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NPPB Property

Melting point:
178-180℃
Boiling point:
523.5±50.0 °C(Predicted)
Density 
1.323±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
ethanol: 3 mg/mL
form 
Yellow solid
pka
2.27±0.22(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N4779
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic acid
Purity
≥98%
Packaging
25mg
Price
$143
Updated
2024/03/01
Sigma-Aldrich
Product number
484100
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic Acid
Packaging
10mg
Price
$130
Updated
2024/03/01
Alfa Aesar
Product number
J67152
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic acid, 98%
Packaging
10mg
Price
$108
Updated
2023/06/20
Alfa Aesar
Product number
J67152
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic acid, 98%
Packaging
50mg
Price
$395
Updated
2023/06/20
Cayman Chemical
Product number
17292
Product name
NPPB
Purity
≥98%
Packaging
10mg
Price
$56
Updated
2024/03/01
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NPPB Chemical Properties,Usage,Production

Uses

NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.

Uses

Biochemical probe primarily as a Cl- channel blocker.

Definition

ChEBI: 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a nitrobenzoic acid.

Biological Activity

Very potent chloride channel blocker.

Biochem/physiol Actions

Potent chloride channel blocker.

storage

Store at RT

NPPB Preparation Products And Raw materials

Raw materials

Preparation Products

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NPPB Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Artis Chemistry (Shanghai) Co. Ltd.
Tel
86-21-60936353
Fax
86-21-60936352
Country
China
ProdList
336
Advantage
58
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7854
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15885
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9708
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
5009
Advantage
55
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9303
Advantage
58

107254-86-4, NPPBRelated Search:


  • 5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID
  • NPPB
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC A CID POTENT CHLORIDE CHANN
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%
  • 3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid
  • Compound 144
  • C13705
  • 5-Nitro-2-(3-phenylpropylamino)benzoic acid,NPPB
  • 5-Nitro-2-(3-phenylpropylaMino)benzoic acid, 5-nitro-2-[(3-phenylpropyl)aMino]benzoic acid, Benzoic acid
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE
  • 5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem
  • Benzoic acid, 5-nitro-2-[(3-phenylpropyl)amino]-
  • Recombinant Human NPPB Protein, His Tag
  • Recombinant Human NT-proBNP/NPPB Protein, His & Flag Tag
  • 107254-86-4
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Chloride Channel Modulators
  • Monovalent Ion Channels
  • Ion Channels
  • Voltage-gated Ion Channels
  • Chloride channel