NPPB

Product Name: NPPB
CAS No.: 107254-86-4
Chemical Name: NPPB
Synonyms: NPPB;ANFB;C13705;Iso-ANP;Compound 144;NPPB, 10 mM in DMSO;NPPB, chloride channel blocker;Gamma-brain natriuretic peptide;Recombinant Human NPPB Protein, His Tag;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE
CBNumber: CB3450426
Molecular Formula: C16H16N2O4
Formula Weight: 300.31
MOL File: 107254-86-4.mol

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NPPB Property

Melting point:: 178-180℃
Boiling point:: 523.5±50.0 °C(Predicted)
Density: 1.323±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: ethanol: 3 mg/mL
form: Yellow solid
pka: 2.27±0.22(Predicted)
color: Light yellow to yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N4779
Product name: 5-Nitro-2-(3-phenylpropylamino)benzoic acid
Purity: ≥98%
Packaging: 25mg
Price: $147
Updated: 2025/07/31

Sigma-Aldrich

Product number: 484100
Product name: 5-Nitro-2-(3-phenylpropylamino)benzoic Acid
Packaging: 10mg
Price: $134
Updated: 2025/07/31

Cayman Chemical

Product number: 17292
Product name: NPPB
Purity: ≥98%
Packaging: 10mg
Price: $56
Updated: 2024/03/01

Cayman Chemical

Product number: 17292
Product name: NPPB
Purity: ≥98%
Packaging: 25mg
Price: $121
Updated: 2024/03/01

Sigma-Aldrich

Product number: N4779
Product name: 5-Nitro-2-(3-phenylpropylamino)benzoic acid
Purity: ≥98%
Packaging: 100mg
Price: $482
Updated: 2025/07/31

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NPPB Chemical Properties,Usage,Production

Uses

NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.

Uses

Biochemical probe primarily as a Cl- channel blocker.

Definition

ChEBI: 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a nitrobenzoic acid.

Biological Activity

Very potent chloride channel blocker.

Biochem/physiol Actions

Potent chloride channel blocker.

storage

Store at RT

NPPB Preparation Products And Raw materials

Raw materials

Preparation Products

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NPPB Suppliers

China 98 Europe 1 Germany 3 India 1 Japan 1 Switzerland 2 United Kingdom 3 United States 16 USA 1 Global 126

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Uchem Inc.

Tel: 15618758386; 15618758386
Fax: QQ:3004479444
Email: sales3@myuchem.com
Country: China
ProdList: 1999
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

MQ (shanghai) Pharmaceuticals Co., Ltd.

Tel: 13761635123
Fax: 1014988033@qq
Email: 1014988033@qq.com
Country: China
ProdList: 4941
Advantage: 55

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9751
Advantage: 58

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

107254-86-4, NPPBRelated Search:

CHLOROTOXIN 2-Chloro-4-nitrotoluene Benzoic acid 2-Nitrobenzoic acid 4-Methoxybenzoic acid Fipronil N-Phenylanthranilic acid Clopamide 2,5-diaminobenzoic acid 2-amino-5-nitro-benzaldehyde RARECHEM AL BI 1183 2-Amino-5-nitrobenzoic acid RARECHEM AL BE 1183 NPPB 2-amino-5-nitrobenzyl alcohol RARECHEM AL BF 1183

5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID

5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID

NPPB

5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC A CID POTENT CHLORIDE CHANN

5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%

3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid

Compound 144

C13705

5-Nitro-2-(3-phenylpropylamino)benzoic acid,NPPB

5-Nitro-2-(3-phenylpropylaMino)benzoic acid, 5-nitro-2-[(3-phenylpropyl)aMino]benzoic acid, Benzoic acid

5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE

5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem

Benzoic acid, 5-nitro-2-[(3-phenylpropyl)amino]-

Recombinant Human NPPB Protein, His Tag

Recombinant Human NT-proBNP/NPPB Protein, His & Flag Tag

NPPB, chloride channel blocker

NPPB, 10 mM in DMSO

Gamma-brain natriuretic peptide

Iso-ANP

ANFB

107254-86-4

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Chloride Channel Modulators

Monovalent Ion Channels

Ion Channels

Voltage-gated Ion Channels

Chloride channel