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NPPB

Product Name
NPPB
CAS No.
107254-86-4
Chemical Name
NPPB
Synonyms
NPPB;C13705;Compound 144;NPPB, chloride channel blocker;Recombinant Human NPPB Protein, His Tag;5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE;5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID;5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID;3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid;5-Nitro-2-(3-phenylpropylamino)benzoic acid,NPPB
CBNumber
CB3450426
Molecular Formula
C16H16N2O4
Formula Weight
300.31
MOL File
107254-86-4.mol
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NPPB Property

Melting point:
178-180℃
Boiling point:
523.5±50.0 °C(Predicted)
Density 
1.323±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
ethanol: 3 mg/mL
form 
Yellow solid
pka
2.27±0.22(Predicted)
color 
Light yellow to yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N4779
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic acid
Purity
≥98%
Packaging
25mg
Price
$143
Updated
2024/03/01
Sigma-Aldrich
Product number
484100
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic Acid
Packaging
10mg
Price
$130
Updated
2024/03/01
Alfa Aesar
Product number
J67152
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic acid, 98%
Packaging
10mg
Price
$108
Updated
2023/06/20
Alfa Aesar
Product number
J67152
Product name
5-Nitro-2-(3-phenylpropylamino)benzoic acid, 98%
Packaging
50mg
Price
$395
Updated
2023/06/20
Cayman Chemical
Product number
17292
Product name
NPPB
Purity
≥98%
Packaging
10mg
Price
$56
Updated
2024/03/01
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NPPB Chemical Properties,Usage,Production

Uses

NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.

Uses

Biochemical probe primarily as a Cl- channel blocker.

Definition

ChEBI: 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a nitrobenzoic acid.

Biological Activity

Very potent chloride channel blocker.

Biochem/physiol Actions

Potent chloride channel blocker.

storage

Store at RT

NPPB Preparation Products And Raw materials

Raw materials

Preparation Products

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NPPB Suppliers

China 71 Europe 1 Germany 3 India 1 Japan 1 Switzerland 2 United Kingdom 3 United States 16 USA 1 Global 99
Labinova AB
Tel
--
Fax
--
Email
info@labinova.se
Country
Europe
ProdList
281
Advantage
64

107254-86-4, NPPBRelated Search:

2-Chloro-4-nitrotoluene Benzoic acid 2-Nitrobenzoic acid 4-Methoxybenzoic acid Fipronil N-Phenylanthranilic acid CHLOROTOXIN Clopamide 2,5-diaminobenzoic acid 2-amino-5-nitro-benzaldehyde RARECHEM AL BI 1183 2-Amino-5-nitrobenzoic acid RARECHEM AL BE 1183 NPPB 2-amino-5-nitrobenzyl alcohol RARECHEM AL BF 1183

  • 5-NITRO-2-(3'-PHENYLPROPYL-AMINO)BENZOIC ACID
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC ACID
  • NPPB
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)BENZOIC A CID POTENT CHLORIDE CHANN
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOIC ACID 98%
  • 3-Nitro-6-[(3-phenylpropyl)amino]benzoic acid
  • Compound 144
  • C13705
  • 5-Nitro-2-(3-phenylpropylamino)benzoic acid,NPPB
  • 5-Nitro-2-(3-phenylpropylaMino)benzoic acid, 5-nitro-2-[(3-phenylpropyl)aMino]benzoic acid, Benzoic acid
  • 5-NITRO-2-(3-PHENYLPROPYLAMINO)-BENZOATE
  • 5-Nitro-2-(3-phenylpropylamino)benzoic Acid - CAS 107254-86-4 - Calbiochem
  • Benzoic acid, 5-nitro-2-[(3-phenylpropyl)amino]-
  • Recombinant Human NPPB Protein, His Tag
  • Recombinant Human NT-proBNP/NPPB Protein, His & Flag Tag
  • NPPB, chloride channel blocker
  • 107254-86-4
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Chloride Channel Modulators
  • Monovalent Ion Channels
  • Ion Channels
  • Voltage-gated Ion Channels
  • Chloride channel