Basic information Safety Supplier Related

N6-(3-Trifluoromethylbenzyl)adenosine

Basic information Safety Supplier Related

N6-(3-Trifluoromethylbenzyl)adenosine Basic information

Product Name:
N6-(3-Trifluoromethylbenzyl)adenosine
Synonyms:
  • N6-(3-Trifluoromethylbenzyl)adenosine
  • Adenosine, N-?[[3-?(trifluoromethyl)?phenyl]?methyl]?-
  • N-(3-trifluoromethylbenzyl)adenosine
  • Antiviral agent 24
CAS:
23661-03-2
MF:
C18H18F3N5O4
MW:
425.36
Mol File:
23661-03-2.mol
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N6-(3-Trifluoromethylbenzyl)adenosine Chemical Properties

form 
Solid
color 
White to off-white
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N6-(3-Trifluoromethylbenzyl)adenosine Usage And Synthesis

Uses

Antiviral agent 24 is a potent antiviral agent with EC50 values of 0.101, 19.9, 91.2 μM for EV71, CVA21, EV68, respectively. Antiviral agent 24 inhibits METTL3/METTL14 activity in a dose-dependent manner[1].

References

[1] Salerno M, et al. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. Eur J Med Chem. 2022 Nov 24;246:114942. DOI:10.1016/j.ejmech.2022.114942

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