Basic information Safety Supplier Related

N6-(3-Methoxybenzyl)-2'-C-methyl adenosine

Basic information Safety Supplier Related

N6-(3-Methoxybenzyl)-2'-C-methyl adenosine Basic information

Product Name:
N6-(3-Methoxybenzyl)-2'-C-methyl adenosine
Synonyms:
  • N6-(3-Methoxybenzyl)-2'-C-methyl adenosine
  • N6-(3-Methoxybenzyl)-2’-C-methyladenosine
  • (2R,3R,4R,5R)-5-(hydroxymethyl)-2-(6-((3-methoxybenzyl)amino)-9H-purin-9-yl)-3-methyltetrahydrofuran-3,4-diol
CAS:
2305415-85-2
MF:
C19H23N5O5
MW:
401.42
Mol File:
2305415-85-2.mol
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N6-(3-Methoxybenzyl)-2'-C-methyl adenosine Chemical Properties

Boiling point:
698.4±65.0 °C(Predicted)
Density 
1.53±0.1 g/cm3(Predicted)
pka
13.18±0.70(Predicted)
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N6-(3-Methoxybenzyl)-2'-C-methyl adenosine Usage And Synthesis

Uses

N6-(3-Methoxybenzyl)-2’-C-methyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

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