6-PHENYL-3(2H)-PYRIDAZINONE Chemical Properties

Melting point:

201-204 °C(lit.)

Density 

1.20±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

11.05±0.40(Predicted)

color 

White to Light yellow

λmax

249nm(HCl aq.)(lit.)

InChIKey

IJUIPRDMWWBTTQ-UHFFFAOYSA-N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2933998090

MSDS

• Language:English Provider:SigmaAldrich

6-PHENYL-3(2H)-PYRIDAZINONE Usage And Synthesis

Uses

6-Phenylpyridazin-3(2H)-one is a reagent in the preparation of cyclase activator Runcaciguat, a compound used in the treatment of kidney disease and non-proliferative diabetic retinopathy.

General Description

6-Phenyl-3(2H)-pyridazinone is a pyridazinone derivative that can be prepared from 4,5- dihydro-6-phenyl-3(2H)-pyridazinone. It is reported to be a weak positive inotropic agent. 6-Phenyl-3(2H)-pyridazinone forms the core of compounds that show a potential antiplatelet activity.

6-PHENYL-3(2H)-PYRIDAZINONE(2166-31-6)Related Product Information

• DICLOMEZINE
• Isamfazone
• ZARDAVERINE
• 4,5-DIHYDRO-6-[4-(1H-IMIDAZOL-1-YL)PHENYL]-3(2H)-PYRIDAZINONE
• Chloridazon
• 5-amino-4-bromo-2-phenyl-3(2h)-pyridazinon
• 4,5-DICHLORO-2-PHENYL-3(2H)-PYRIDAZINONE
• 4-Chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-3(2H)-pyridazinone,4-chloro-5-(methylamino)-2-(3-(trifluoromethyl)phenyl)-3(2h)-pyridazinon
• 5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE
• 6-HYDROXY-2-PHENYL-3(2H)-PYRIDAZINONE
• 4,5-DIBROMO-2-PHENYL-3(2H)-PYRIDAZINONE
• 2,3,4,5-TETRAHYDRO-6-PHENYL-3(2H)-PYRIDAZINONE,4,5-DIHYDRO-6-PHENYL-3(2H)-PYRIDAZINONE
• 5-CHLORO-2-METHYL-6-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE
• 6(4-BROMOPHENYL)-3(2H)PYRIDAZINONE
• 6-PHENYL-3(2H)-PYRIDAZINONE-4-CARBOXYLIC ACID ETHYL ESTER
• 6-PHENYL-3(2H)-PYRIDAZINONE
• 6-METHYL-2-PHENYL-3-(2H)-PYRIDAZINONE
• 4-AMINO-6-PHENYL-3(2H)-PYRIDAZINONE