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Propargyl p-toluenesulfonate

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Propargyl p-toluenesulfonate Basic information

Product Name:
Propargyl p-toluenesulfonate
Synonyms:
  • prop-2-ynyl 4-methylbenzenesulfonate
  • Propargyl p-toluenesulfonate >=97.0% (GC)
  • PROPARGYL P-TOLUENESULFONATE
  • PROPARGYL TOSYLATE
  • PROPARGYL P-TOLUENESULPHONATE
  • P-TOLUENESULFONIC ACID PROPARGYL ESTER
  • 2-propyn-1-ol,4-methylbenzenesulfonate
  • Propargylp-toluenesulfonate,97%
CAS:
6165-76-0
MF:
C10H10O3S
MW:
210.25
Product Categories:
  • Acetylenes
  • Acetylenic Alcohols & Their Derivatives
  • Organic Building Blocks
  • Sulfur Compounds
  • Tosylates
Mol File:
6165-76-0.mol
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Propargyl p-toluenesulfonate Chemical Properties

Boiling point:
117-121°C 0,3mm
Density 
1.215 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.530
Flash point:
117-121°C/0.3mm
storage temp. 
2-8°C
solubility 
soluble in Chloroform, Dichloromethane, DMSO, Ethyl Acetate
form 
Liquid
color 
Clear colorless to brown
Water Solubility 
Soluble in Chloroform, Dichloromethane, DMSO, Ethyl Acetate. Not miscible in water.
BRN 
1212957
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
XT7300000
4.10-10-21
HS Code 
29041000

MSDS

  • Language:English Provider:ACROS
  • Language:English Provider:ALFA
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Propargyl p-toluenesulfonate Usage And Synthesis

Chemical Properties

Clear colorless to brown liquid

Uses

Propargyl p-toluenesulfonate is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Uses

Propargyl p-toluenesulfonate can be used as an initiator in the synthesis of linear and cyclic poly(2-isopropyl-2-oxazoline)s by cationic ring-opening polymerization of 2-isopropyl-2-oxazoline.
It can also be used as a reagent to synthesize:

  • 2-hydroxy-4-pentynoic acid by an alkylation reaction with diethyl 2-acetamidomalonate followed by subsequent hydrolysis, decarboxylation, diazotization, and hydroxylation reactions.
  • Furan derivatives by Pd-catalyzed reaction with acylchromates.

Uses

Protected Propargyl. A possible genotoxic compound that can affect the bacterial and mammalian cell systems.

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