3-Thiazolidineacetic acid, 4-oxo-2-thioxo-, methyl ester Chemical Properties

Boiling point:

302.1±44.0 °C(Predicted)

Density 

1.50±0.1 g/cm3(Predicted)

pka

-2.36±0.20(Predicted)

InChI

InChI=1S/C6H7NO3S2/c1-10-5(9)2-7-4(8)3-12-6(7)11/h2-3H2,1H3

InChIKey

IQPKPVIMMTUWNT-UHFFFAOYSA-N

SMILES

S1CC(=O)N(CC(OC)=O)C1=S

3-Thiazolidineacetic acid, 4-oxo-2-thioxo-, methyl ester Usage And Synthesis

Uses

Methyl 2-(4-oxo-2-thioxothiazolidin-3-yl)acetate is an intermediate of Epalrestat (E565300). Epalrestat is an aldose reductase inhibitor used in the treatment of diabetic neuropathy.

3-Thiazolidineacetic acid, 4-oxo-2-thioxo-, methyl ester(149789-77-5)Related Product Information

• Epalrestat Impurity 4
• 3-Thiazolidineaceticacid, 4-oxo-2-thioxo-, ethyl ester
• (5-BENZYLIDENE-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL)-ACETIC ACID
• (Z)-2-methyl-3-phenylacrylaldehyde
• SB 206328
• 4-Bromomethylbenzoic acid
• Epalrestat
• 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid
• (Z)-2-(5-benzylidene-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
• Rhodanine-3-acetic acid
• Methyl (E)-3-[2-Butyl-1-[(4-Carbomethoxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoate
• Eprosartan related coMpound C
• 3-(2-THIENYL)PROPIONIC ACID
• (2-CHLORO-ACETYLAMINO)-ACETIC ACID METHYL ESTER
• ethyl 2-((E)-5-((E)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetate
• α-Methylcinnamaldehyde
• 4-(Hydroxymethyl)benzoic acid
• Epalrestat iMpurity