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Myricitrin

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Myricitrin Basic information

Product Name:
Myricitrin
Synonyms:
  • CANNABISCITRIN
  • 5,7-dihydroxy-3-((2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-(3,4,5-trihydroxy-phenyl)-1-benzopyran-4-one
  • MYRICETIN-3-O-RHAMNOSIDE
  • MYRICETIN-3-O-RHAVINOSIDE
  • MYRICETIN-3-RHAMNOSIDE
  • MYRICITRIN
  • 3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-one
  • Myricetrin
CAS:
17912-87-7
MF:
C21H20O12
MW:
464.38
EINECS:
241-856-7
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • Nutritional Ingredients
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Flavanols
  • Aromatics
  • Carbohydrates & Derivatives
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • sy
Mol File:
17912-87-7.mol
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Myricitrin Chemical Properties

Melting point:
197°C(lit.)
Boiling point:
896.6±65.0 °C(Predicted)
Density 
1.88±0.1 g/cm3(Predicted)
FEMA 
4491 | MYRICITRIN
storage temp. 
-20°C
solubility 
Soluble to 93 mg/mL (200.26 mM) in DMSO
pka
6.16±0.40(Predicted)
color 
Light yellow to Yellow to Orange
Odor
bayberry waxy
JECFA Number
2207
LogP
1.98
CAS DataBase Reference
17912-87-7(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29389090
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Myricitrin Usage And Synthesis

Chemical Properties

White to light yellow powder

Uses

It was isolated from the leaves of Myrtus communis an inhibitory activity against nifuroxazide, aflatoxine B1 and H2O2 induced mutagenicity. Antioxidant

Uses

It was isolated from the leaves of Myrtus communis; shows antimutagenic activity. Myricitrin was a very potent radical scavenger with an IC50 value of 1.4 .mu.g/mL. Moreover, this compound induced an inhibitory activity against nifuroxazide, aflatoxine B1 and H2O2 induced mutagenicity. Antioxidant.

Uses

Myricitrin may be used as an analytical reference standard for determination of the analyte in Folium Rhododendri Micranthi extract using high-performance liquid chromatography. It may also be used as an external standard in the validation of both commercial herbal medicines and crude material of Myrcia uniflora extracts using high-performance liquid chromatography technique.

Definition

ChEBI: A glycosyloxyflavone that consists of myricetin attached to a alpha-L-rhamnopyranosyl residue at position 3 via a glycosidic linkage. Isolated from Myrica cerifera, it exhibits anti-allergic activity.

General Description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Biochem/physiol Actions

The metabolite myricitrin, 3-O-rhamnoside of myricetin, is found in plants, e.g. in the bark of Myrica esculenta (Myricaceae) and in the leaves of Myrica gale and in Chrysobalanus icaco. It is a feeding stimulant for some leaf beetles; and shown to have strong antioxidant activity against DPPH. Myricitrin may be of potential interest in the management of inflammatory conditions, and could constitute an attractive molecule of interest for the development of new analgesic drugs. Myricitrin is a nitric oxide (NO) and protein kinase C (PKC) inhibitor that has central nervous system activity, including anxiolytic-like action.

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