(2-pyridyldithio)-PEG4-propargyl Chemical Properties

Boiling point:

465.6±45.0 °C(Predicted)

Density 

1.18±0.1 g/cm3(Predicted)

pka

1.81±0.12(Predicted)

(2-pyridyldithio)-PEG4-propargyl Usage And Synthesis

Description

(2-pyridyldithio)-PEG4-propargyl is a PEG linker which contains a pyridyl disulfide moiety and a propargyl group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH levels. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.

(2-pyridyldithio)-PEG4-propargyl(2170240-99-8)Related Product Information

• SPDP-PEG4-NHS ester
• 1,3-Etheno-2H-isoindole-2-pentanoic acid, 1,3-dihydro-δ-oxo
• (2-pyridyldithio)-PEG2-t-butyl ester
• (2-pyridyldithio)-PEG4-alcohol
• Naphthalen-1,4-iMine-9-carboxylic acid, 1,4-dihydro-, 1,1-diMethylethyl ester