Basic information Safety Supplier Related

(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine

Basic information Safety Supplier Related

(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine Basic information

Product Name:
(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine
Synonyms:
  • (1R,2R)-(-)-N1,N2-Dimethylcyclohexane-1,2-diamine 95%
  • (1S,2S)-N1,N2-dimethylcyclohexane-1,2-diamine
  • (1R,2R)-(-)-1,2-BIS(METHYLAMINO)CYCLOHEXANE
  • (1R,2R)-1,2-BIS(METHYLAMINO)CYCLOHEXANE
  • (1R,2R)-(-)-N,N'-DIMETHYLCYCLOHEXANE-1,2-DIAMINE
  • (1R,2R)-N,N'-DIMETHYL-1,2-CYCLOHEXANEDIAMINE
  • (1R,2R)-DIAMINOMETHYLCYCLOHEXANE
  • trans-1,2-Bis(methylamino)cyclohexane, (R,R)-(-)-N,Nμ-Dimethyl-1,2-diaminocyclohexane
CAS:
68737-65-5
MF:
C8H18N2
MW:
142.24
Product Categories:
  • Chiral Building Blocks
  • e.e. / Absolute Configuration Determination (NMR)
  • Amines and Anilines
  • Amines (Chiral)
  • Enantiomer Excess & Absolute Configuration Determination
  • Synthetic Organic Chemistry
  • chiral
  • Analytical Chemistry
  • Chiral Nitrogen
  • DACH&Trost Series
Mol File:
68737-65-5.mol
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(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine Chemical Properties

Melting point:
39-44 °C
alpha 
-145 º (c=4.47 in chloroform)
Boiling point:
249.85°C (rough estimate)
Density 
0.902
refractive index 
-140 ° (C=4, CHCl3)
Flash point:
74 °C
storage temp. 
2-8°C
form 
Low Melting Solid
pka
11.04±0.40(Predicted)
color 
White to light yellow
optical activity
[α]/D -145±5°, c = 4.47 in chloroform
InChIKey
JRHPOFJADXHYBR-HTQZYQBOSA-N
CAS DataBase Reference
68737-65-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
34-22
Safety Statements 
45-36/37/39-25-26
RIDADR 
3259
WGK Germany 
3
HazardClass 
8
PackingGroup 
HS Code 
29213000

MSDS

  • Language:English Provider:ACROS
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(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

(R,R)-(?)-N,N′-Dimethyl-1,2-cyclohexanediamine can be used:

  • As a ligand in the preparation of 4H-benzo[f]imidazo[1,4]diazepin-6-one through multi-component Ullmann coupling reaction.
  • In one of the key synthetic steps for the preparation of tricyclic γ-secretase modulators.
  • To prepare chiral fluorous diamino-diol proligand, which is used in the synthesis of zirconium metal complexes applicable as catalysts in 1-hexene polymerization.

General Description

(R,R)-(-)-N,N′-Dimethyl-1,2-cyclohexanediamine is a N,N′-dimethylated derivative of enantiopure 1,2-diaminocyclohexane. It can be formed during the hydrolysis of (R3a,R7a)-1,3-(dimethyl)-2-phenyl-2,3,3a,4,5,6,7,7a-octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide using HCl-methanol.

(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamineSupplier

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