Basic information Safety Supplier Related

(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid

Basic information Safety Supplier Related

(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid Basic information

Product Name:
(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid
Synonyms:
  • D-THREO-HYDROXYLEUCINE
  • (2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid,99.5+%,99+% ee
  • (2R,3S)-(-)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID, 99+% E.E., 99.5+%
  • d(-)-threo-3-hydroxyleucine
  • (2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid
  • (2R,3S)-β-Hydroxyleucine
  • (3S)-3-Hydroxy-D-leucine
  • threo-3-Hydroxy-D-leucine
CAS:
87421-23-6
MF:
C6H13NO3
MW:
147.17
Product Categories:
  • Amino Acids & Derivatives
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • unnatural amino acids
Mol File:
87421-23-6.mol
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(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid Chemical Properties

Melting point:
205 °C
alpha 
-19.4 º (c=2, 6N HCl 25 ºC)
Boiling point:
267.28°C (rough estimate)
Density 
1.2006 (rough estimate)
refractive index 
1.4240 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
Water Solubility 
soluble
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Safety Information

Safety Statements 
24/25
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(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acid Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

(2R,3S)-β-Hydroxyleucine is a nonprotein amino acid. (2R,3S)-β-Hydroxyleucineis an inhibitor of serine protease. In particular, (2R,3S)-β-Hydroxyleucine was effective in inhibiting trypsin and proteinase K of the serine proteases group. (2R,3S)-β-Hydroxyleucine was not able to inhibit the growth of gram-positive and gram-negative bacteria and yeasts unlike its (2S,3R)-isomer.

(2R,3S)-(-)-2-Amino-3-hydroxy-4-methylpentanoic acidSupplier

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