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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Amino Acids and Derivatives >  Other amino acid derivatives >  (2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid

(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid

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(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid Basic information

Product Name:
(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid
Synonyms:
  • (2S,3R)-(+)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID, 99+% E.E., 99
  • L-THREO-HYDROXYLEUCINE
  • (2S,3R)-3-Hydroxyleucine
  • 3-Hydroxy-L-Leucine
  • L(+)-THREO-3-HYDROXYLEUCINE
  • (2S,3R)-(+)-2-Amino-3-hydroxy-4-methyl-pentanoicacid(e.e.)
  • (2S3R)-(+)-2-AMINO-3-HYDROXY-4-METHYL- PENTANOIC ACID 98%
  • (2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid
CAS:
10148-71-7
MF:
C6H13NO3
MW:
147.17
Product Categories:
  • unnatural amino acids
  • Amino Acid Derivatives
Mol File:
10148-71-7.mol
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(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid Chemical Properties

Melting point:
225-227 °C
alpha 
18.5 º (c=1, 6N HCl 25 ºC)
Boiling point:
267.28°C (rough estimate)
Density 
1.2006 (rough estimate)
refractive index 
1.4240 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.40±0.25(Predicted)
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Safety Information

Safety Statements 
24/25-olubility-Solubility-S24/25
HS Code 
29224985
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(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid Usage And Synthesis

Chemical Properties

white fluffy powder

Uses

(2S,3R)-β-Hydroxyleucine is a nonprotein amino acid. (2S,3R)-β-Hydroxyleucineis an inhibitor of serine protease. In particular, (2S,3R)-β-Hydroxyleucine was effective in inhibiting trypsin and protein ase K of the serine proteases group. (2S,3R)-β-Hydroxyleucine is able to inhibit the growth of gram-positive and gram-negative bacteria and yeasts unlike its (2R,3S)-isomer.

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