BENZOTRIPT Chemical Properties

storage temp. 

-20°C

solubility 

Soluble in DMSO (up to at least 25 mg/ml)

form 

solid

color 

White

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

BENZOTRIPT Usage And Synthesis

Description

Benzotript (39544-74-6) antagonizes the interaction of cholecystokinin and related peptides with the cholecystokinin receptor.1 ?It has been reported to potentiate morphine analgesia via interaction with opioid receptors.2

Uses

Benzotript is an antiulcer drug that is a cholecystokinin receptor (CCK-2R) antagonist .

References

1) Hahne (1981), Proglumide and benzotript: Members of a different class of cholecystokinin receptor antagonists; Proc. Natl. Acad. Sci. USA. 78 6304 2) Gaudreau et al. (1990), Cholecystokinin antagonists proglumide, lorglumide and benzotript, but not L-364,718, interact with brain opioid binding sites; Neuropeptides 16 51

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