Yellow pyoctanine Chemical Properties

Melting point:

138℃

Boiling point:

400.55°C (rough estimate)

Density 

1.01

refractive index 

1.6360 (estimate)

pka

10.12±0.50(Predicted)

Colour Index 

41000B

BRN 

2215338

CAS DataBase Reference

492-80-8(CAS DataBase Reference)

IARC

2B (Vol. 1, Sup 7, 99, 100F) 2012

EPA Substance Registry System

Auramine (492-80-8)

Safety Information

Hazard Codes 

Xn,N

Risk Statements 

22-36-40-51/53

Safety Statements 

36/37-61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

BY3500000

Hazardous Substances Data

492-80-8(Hazardous Substances Data)

Yellow pyoctanine Usage And Synthesis

Description

Auramine is a yellow crystalline powder or flaky material. Molecular weight= 267.4; Freezing/Meltingpoint=136℃. Hazard Identification (based on NFPA-704M Rating System): Health 3, Flammability 1, Reactivity 0;(hydrochloride) Health 3, Flammability 0, Reactivity 0.Insoluble in water.

Chemical Properties

Auramine is a yellow crystalline powder or flaky material.

Uses

Yellow dye for paper, textiles, leather; antisep- tic; fungicide.

Preparation

(a) will Sulphur dissolved in 4-(4-(Dimethylamino)benzyl)-N,N-dimethylbenzenamine?methane. Add in ammonia and sodium chloride, ammonia in 175 ℃ heat the mixture, with hot water extraction dye and salting out (GP53614); (b) Bis (4 – (dimethylamino) phenyl) methanone and ammonia and Zinc chloride in a total of 150 ~ 160 ℃ heat (GP 29060). Free base is to add the same amount of naoh aqueous solution hydrochloride, sodium carbonate and ammonia and have to.

Definition

ChEBI: A member of the class of imines that is benzophenone imine carrying two dimethylamino substituents at positions 4 and 4'. The hydrochloride salt is the biological stain 'auramine O'

General Description

Yellow crystalline powder or yellow needles.

Reactivity Profile

Yellow pyoctanine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Hazard

Confirmed carcinogen.

Health Hazard

Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution.

Fire Hazard

Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.

Agricultural Uses

Fungicide: Auramine is used industrially as a dye or dye intermediate for coloring textiles, paper, and leather. Also used as an antiseptic (a powerful antiseptic in ear and nose surgery and in gonorrhea treatment)

Trade name

WAXOLINE YELLOW O®

Potential Exposure

Auramine is used industrially as a dye or dye intermediate for coloring textiles; paper, and leather. Also used as an antiseptic (a powerful antiseptic in ear and nose surgery, and treatment of gonorrhea) and fungicide. Human exposure to auramine occurs principally through skin absorption or inhalation of vapors. Low-level dermal exposure to the consumer may occur but would be limited to any migration of auramine from fabric, leather, or paper goods.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

storage

Color Code—Blue: Health Hazard/Poison: Store ina secure poison location. Prior to working with auramineyou should be trained on its proper handling and storage.Store in tightly closed containers in a cool, well-ventilatedarea away from oxidizers. Sources of ignition, such as smoking and open flames, are prohibited where this chemical isused, handled, or stored in a manner that could create apotential fire or explosion hazard. A regulated, marked areashould be established where this chemical is handled, used,or stored in compliance with OSHA Standard 1910.1045.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Properties and Applications

brilliant green yellow. Soluble in cold water, soluble in hot water for brilliant yellow, boils part decomposition, soluble in ethanol for yellow. In concentrated sulfuric acid to colorless, dilution after buff. The dye for C.I. Basic Yellow 2 free base. Used for oil, paraffin wax, alcohol solvent, alcohol soluble paint, printing ink color.

Standard	Light Fastness	Heat-resistant(℃)		water	Sodium Carbonate(5%)	Hydrochloric acid(5%)
		Melting point	Stable
ISO	Poor	120	70≥100 Sublimation	Poor	Good	General

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incinerate in furnace with afterburner and scrubber.

Yellow pyoctanine(492-80-8)Related Product Information

• benzenesulphonic acid, compound with p,p'-carbonimidoylbis[N,N-dimethylaniline]
• Yellow pyoctanine
• AURORA KA-777
• 3-Methyl(bis(4-(dimethylamino)phenyl)methylene)hydrazone-2(3H)-benzothiazolone
• AURAMINE O