Basic information Safety Supplier Related

Fazarabine

Basic information Safety Supplier Related

Fazarabine Basic information

Product Name:
Fazarabine
Synonyms:
  • Fazarabine
  • 4-amino-1-beta-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one
  • 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
  • 4-Amino-1-β-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one
  • ara-AC
  • NSC-281272
  • 1,3,5-Triazin-2(1H)-one, 4-amino-1-β-D-arabinofuranosyl-
  • 4-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one
CAS:
65886-71-7
MF:
C8H12N4O5
MW:
244.2
Mol File:
65886-71-7.mol
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Fazarabine Chemical Properties

Melting point:
220 °C (decomp)
Boiling point:
534.5±60.0 °C(Predicted)
Density 
2.08±0.1 g/cm3(Predicted)
pka
13.46±0.70(Predicted)
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Fazarabine Usage And Synthesis

Uses

Antineoplastic.

Definition

ChEBI: Fazarabine is an N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-arabinofuranosyl residue via an N-glycosidic linkage. A synthetic analogue of cytosine arabinoside and 5-azacytidine that incorporates structural features of both compounds, it shows good activity against a variety of transplanted tumors. It has a role as an antineoplastic agent. It is a N-glycosyl-1,3,5-triazine and a nucleoside analogue. It is functionally related to a beta-D-arabinofuranose.

FazarabineSupplier

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ANHUI WITOP BIOTECH CO., LTD
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