etamiphyllin Chemical Properties

Melting point:

75°

Boiling point:

422.11°C (rough estimate)

Density 

1.1155 (rough estimate)

refractive index 

1.6050 (estimate)

pka

9.85±0.25(Predicted)

etamiphyllin Usage And Synthesis

Originator

Dalophylline,Arnolds Veterinary

Definition

ChEBI: Etamiphylline is an oxopurine.

Manufacturing Process

One mol of theophylline was dissolved in a 1% aqueous solution of 1 mol of caustic soda. One mol of β-diethylaminoethyl chloride was added, and the mixture was boiled for 6 hours with reflux, while stirring.
The product was evaporated to dryness in vacuum, and the dry, pasty residue was taken up in acetone, to separate the desired compound from sodium chloride associated therewith. The acetone solution was distilled to remove solvent and 1,3-dimethyl-7-(β-diethylamino)ethylxanthine-7-(β- (diethylamino)ethyl)theophylline was obtained as a white mass. MP: 74°C. The product is very soluble in water, alcohol and acetone.

Therapeutic Function

Diuretic, Cardiotonic, Smooth muscle relaxant, Respiratory stimulant

etamiphyllin(314-35-2)Related Product Information

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• 7-[2-(2,6-DIMETHYLMORPHOLIN-4-YL)-2-OXOETHYL]-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE
• N,N-DIALLYL-2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)ACETAMIDE
• 7-[2-(3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-2-OXOETHYL]-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE
• SALOR-INT L343404-1EA