Stamulumab
Stamulumab Basic information
- Product Name:
- Stamulumab
- Synonyms:
-
- STAMULUMAB
- Myo 029
- Myo-029
- Research Grade Stamulumab (DHA30604)
- Research Grade Stamulumab
- CAS:
- 705287-60-1
- MW:
- 0
- Product Categories:
-
- Pharmaceutical intermediate
- Mol File:
- Mol File
More
Less
Stamulumab Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
More
Less
Stamulumab Usage And Synthesis
Uses
Treatment of muscular dystrophy and age-related sarcopenia or frailty.
in vivo
Stamulumab (MYO-029; ip; 1-10 mg/kg/week for 12 weeks) increases skeletal muscle mass in vivo in a concentration-dependent manner in SCID mice. Stamulumab leads to muscle fiber hypertrophy and not hyperplasia[1].
Stamulumab (i.v.; 1, 5, 20, 100 mg/kg/week for 4 weeks) has a central clearance (CL) of 0.25 mL/h/kg in C57/SCID mice[1].
Pharmacokinetic Parameters of Stamulumab (MYO-029)[1].
| C57/SCID mice IV (1-100 mg/kg/week for 4 weeks) | Sprague Dawley rats (2-50 mg/kg; single injection) | Cynomolgus monkeys (10-100 mg/kg/week for 5 or 39 weeks) | |
| CL (mL/h/kg) | 0.245 | 0.542 | 0.228 |
| Volume of central compartment (mL/kg) | 103 | 58.9 | 41.8 |
| Distributive clearance (mL/h/kg) | 1.79 | 0.815 |
| Animal Model: | Female SCID mice[1] |
| Dosage: | 1, 2.5, 5, 10 mg/kg |
| Administration: | IP; every week for 12 weeks |
| Result: | Increased skeletal muscle mass in vivo in a concentration‐dependent manner. |
StamulumabSupplier
Guangzhou Hongyuan Chemical Co.,Ltd
- Tel
- 15817493340
- 981810490@qq.com
Wuhan Chemstan Biotechnology Co., Ltd.
- Tel
- 027-65317797 15926423062
- 422450190@qq.com
Biolab Reagents
- Tel
- 027-65279366 18108604356
- products@biolabreagent.com
Wuhan Jingkangen Biomedical Technology Co., Ltd
- Tel
- 13720134139 086-15871494362 13720134139
- orders@jknbiochem.com
Shanghai Yifei Biotechnology Co. , Ltd.
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com