Butin Chemical Properties

Melting point:

224-226℃

Boiling point:

582.4±50.0 °C(Predicted)

Density 

1.485

storage temp. 

2-8°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

7.69±0.40(Predicted)

color 

Yellow to brown

Butin Usage And Synthesis

Uses

(-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities[1][2].

Definition

ChEBI: Butin is a trihydroxyflavanone in which the three hydroxy substituents are located at positions 3', 4' and 7. It is found in Acacia mearnsii, Vernonia anthelmintica and Dalbergia odorifera and has a protective affect against oxidative stress-induced mitochondrial dysfunction. It has a role as an antioxidant, a protective agent and a metabolite. It is a trihydroxyflavanone and a member of 4'-hydroxyflavanones.

References

[1] Duan J, et al. Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway. Sci Rep. 2017 Jan 27;7:41491. DOI:10.1038/srep41491
[2] Li P, et al. Butin Attenuates Brain Edema in a Rat Model of Intracerebral Hemorrhage by Anti Inflammatory Pathway. Transl Neurosci. 2018 May 8;9:7-12. DOI:10.1515/tnsci-2018-0002

Butin(492-14-8)Related Product Information

• VIOLURIC ACID
• corytuberine
• Camphor benzalkonium methosulfate
• BUTEIN
• 2,3-DIHYDROROBINETIN
• DIHYDROFISETIN
• Dihydromyricetin
• ERIOCITRIN
• 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVANONE
• ERIODICTYOL-7-GLUCOSIDE
• ERIODICTYOL
• HESPERETIN
• Hesperidin
• NEOERIOCITRIN
• TAXIFOLIN
• HOMOERIODICTYOL
• (+)-TAXIFOLIN
• (+/-)-TAXIFOLIN