picromycin Chemical Properties

Melting point:

169.5℃

alpha 

D24 +8.2° (c = 3.5 in ethanol); D20 -33.5° (c = 2.07 in chloroform); D24 -50.2° (c = 6.3 in chloroform)

storage temp. 

Store at -20°C

solubility 

DMSO: soluble

form 

A crystalline solid

Boiling point:

688.1±55.0 °C(Predicted)

Density 

1.14±0.1 g/cm3(Predicted)

pka

11.15±0.70(Predicted)

color 

White crystalline

picromycin Usage And Synthesis

Uses

Pikromycin is an inhibitor of Prolyl endopeptidase.

Definition

ChEBI: A macrolide antibiotic that is biosynthesised by Streptomyces venezuelae.

Enzyme inhibitor

This polyketide (FW = 525.68 g/mol; CAS 19721-56-3; bitter-tasting solid; low water solubility; soluble in benzene and acetone) from Actinomyces spp., and originally spelled pikromycin, was the first identified macrolide antibiotic. Picromycin is most likely produced as the inactive diglucoside and liberated extracellularly as the active antibiotic through the action of a b-glucosidase.

storage

+4°C

picromycin(19721-56-3)Related Product Information

• ACETOACETIC ACID SEC-BUTYL ESTER
• METHYL 2,4-DIMETHYL-3-OXOPENTANOATE
• Isobutyl acetoacetate
• Methyl isobutyrylacetate
• METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL
• Ethyl isobutyrylacetate
• 3-BUTENE-1,2-DIOL
• Telithromycin intermediate (7A)
• METHYL 8-METHYLNONANOATE
• ETHYL 4-METHYLOCTANOATE
• propyl 2-methylpentanoate
• 3-METHYL-1-PENTEN-3-OL
• FEMA 2200
• ETHYL 10-UNDECENOATE
• ACETOACETIC ACID N-PROPYL ESTER
• delta-Nonalactone
• 4-ISOBUTOXY-2-BUTANONE
• Ethyl butyrylacetate