INTERMEDINE
INTERMEDINE Basic information
- Product Name:
- INTERMEDINE
- Synonyms:
-
- INTERMIDINE
- (1R)-2,3,5,7aβ-Tetrahydro-7-[[(2S,3R)-2-isopropyl-2,3-dihydroxybutyryl]oxymethyl]-1H-pyrrolizine-1-ol
- (2S,3R)-2,3-Dihydroxy-2-isopropylbutanoic acid [[(5R,6R)-6-hydroxy-1-azabicyclo[3.3.0]oct-3-en-4-yl]methyl] ester
- 9-(+)-Trachelanthylretronecine
- C10330
- Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-
- (+)-Intermedine
- CAS:
- 10285-06-0
- MF:
- C15H25NO5
- MW:
- 299.36
- Mol File:
- 10285-06-0.mol
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INTERMEDINE Chemical Properties
- Melting point:
- 140-141 °C
- Boiling point:
- 463.3±45.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- pka
- 12.59±0.29(Predicted)
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INTERMEDINE Usage And Synthesis
Uses
Intermedine-D7 is a labelled analogue of Intermedine (I666660). Intermedine is an unsaturated monoester pyrrolizidine alkaloid that is extracted from the seeds of Amsinckia intermedia, a tarweed that causes enzootic hepatic cirrhosis in horses and hard liver disease in cattle. Intermedine is also a diastereomer of Lycopsamine (L487525), a pyrrolizidine alkaloid that is found in honey and in comfrey (a topical anti-inflammatory agent used to treat patients with arthritis and gout).
Definition
ChEBI: A carboxylic ester compound formed from condensation between retronecine and (2S,3R)-2,3-dihydroxy-2-isopropylbutanoic acid.
INTERMEDINESupplier
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