4-FLUORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE Chemical Properties

Boiling point:

48 °C1 mm Hg(lit.)

Density 

1.44 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.461(lit.)

Flash point:

176 °F

InChI

1S/C8H3F4NO/c9-7-2-1-5(13-4-14)3-6(7)8(10,11)12/h1-3H

InChIKey

OPPYFFRLKJUEOS-UHFFFAOYSA-N

SMILES

Fc1ccc(cc1C(F)(F)F)N=C=O

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36/37/39

RIDADR 

UN 2922 8/PG 1

WGK Germany 

3

HS Code 

29291090

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
Skin Sens. 1
STOT SE 3

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

4-FLUORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

4-Fluoro-3-(trifluoromethyl)phenyl isocyanate may be used in the synthesis of the following:

• pyrazine and pyrimidine analogs of biarylamines
• N-[trans-5-(3-cyanophenyl)bicyclo[3.1.0]hex-2-yl]-N′-[4- fluoro-3-(trifluoromethyl)phenyl]-N-[2-(3(R)-hydroxy-1-pyrrolidinyl]ethyl]urea
• N-[trans-5-(3-cyanophenyl)bicyclo[3.1.0]hex-2-yl]-N′-[4- fluoro-3-(trifluoromethyl)phenyl]-N-[2-(4-methyl-1-piperazinyl)- ethyl]urea

4-FLUORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE(139057-86-6)Related Product Information

• 2-FLUORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
• 2-IODOPHENYL ISOCYANATE
• 2-PHENOXYPHENYL ISOCYANATE
• 4-BROMO-2-CHLOROPHENYL ISOCYANATE
• 3,4-DICHLOROBENZYL ISOCYANATE
• 4-BROMO-2-FLUOROPHENYL ISOCYANATE
• 3-CHLORO-4-FLUOROPHENYL ISOCYANATE
• Isobutyl isocyanate
• Hexamethylene Diisocyanate
• 3-Cyanophenyl isocyanate
• 2-FLUORO-5-METHYLPHENYL ISOCYANATE
• 2-ETHYLHEXYL ISOCYANATE 98
• 2,3-DIMETHYLPHENYL ISOCYANATE
• 4-CHLORO-2-FLUOROPHENYL ISOCYANATE 97
• 4-(METHYLTHIO)PHENYL ISOCYANATE
• 2-CHLORO-4-(TRIFLUOROMETHYL)PHENYL
• 2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL ISOCYANATE,2-Fluoro-5-(trifluoromethyl)phenyl isocyanate 97%
• 2-FLUORO-6-(TRIFLUOROMETHYL)PHENYL ISOCYANATE,2-FLUORO-6-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 97%