- Product Name:
- Hexamethylene Diisocyanate
- 1,6-HEXAMETHYLENE DIISOCYANATE
- HEXAMETHYLENE DIISOCYANATE
- Evafanol AS-1
- Hexamethylene diisocyanate, 1,6-? hexane 1,6-diisocyanate
- Product Categories:
- Isocyanate Monomers
- Building Blocks
- Chemical Synthesis
- Materials Science
- Nitrogen Compounds
- Organic Building Blocks
- Polymer Science
- Mol File:
Hexamethylene Diisocyanate Chemical Properties
- Melting point:
- Boiling point:
- 82-85 °C0.1 mm Hg
- 1.047 g/mL at 20 °C(lit.)
- vapor pressure
- 0.05 mm Hg ( 25 °C)
- refractive index
- n20/D 1.453
- Flash point:
- 248 °F
- storage temp.
- Clear colorless to slightly yellow
- Specific Gravity
- explosive limit
- Water Solubility
- Moisture Sensitive
- Exposure limits
- TLV-TWA 0.0343 mg/m3 (0.005 ppm) (ACGIH).
- Stable. Moisture sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases, amines, acids. May react explosively with alcohols in the presence of base without a diluting solvent. Heating above 200 C may cause polymerization.
- CAS DataBase Reference
- 822-06-0(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,6-Hexamethylene diisocyanate(822-06-0)
- EPA Substance Registry System
- Hexamethylene-1,6-diisocyanate (822-06-0)
- Hazard Codes
- Risk Statements
- Safety Statements
- UN 2281 6.1/PG 2
- WGK Germany
- Autoignition Temperature
- 454 °C
- HS Code
- Hazardous Substances Data
- 822-06-0(Hazardous Substances Data)
- LD50 orally in Rabbit: 746 mg/kg LD50 dermal Rabbit 570 mg/kg
Hexamethylene Diisocyanate Usage And Synthesis
This diisocyanate compound is used in the manufacture of various polyurethane products: elastic and rigid foams, paints, lacquers, adhesives, bin ding agents, synthetic rubbers, and elastomeric fibers.
Hexamethylene diisocyanate is a colorless liquid. Sharp, irritating odor.
1,6-Hexamethylenediisocyanate is a chemical intermediate used in the production of urethane products.
Cross-linking agent (hardener) in the production of polyurethane materials such as car paints, dental materials, and contact lenses
Hexamethylene diisocyanate (HDI) is one of the most common aliphatic disocyanates, It is a monomer used in the production of polyurethane foams and exceptionally high-quality coatings, and is found in some industrial paints and spray painting operations. It is a compound which reacts readily with water and alcohols (Von Burg 1993). It has a vapor pressure of 0.05 mm Hg at room temperature, but can be present in aerosol form allowing a potentially higher exposure to individuals. The HDI-BT trimer is often present for similar industrial uses. It would be expected to have a lower vapor pressure; however, the aerosol form can also be present, allowing potentially higher exposure of HDI-BT to individuals. Hexamethylene diisocyanate reacts slowly with water to form carbon dioxide (HSDB 1996). The base-catalyzed reaction of Hexamethylene diisocyanate with alcohols should be carried out in inert solvents; the reaction may occur with explosive violence in the absence of solvents (NFPA 1994).
ChEBI: A diisocyanate compound with the two isocyanates linked by a hexane-1,6-diyl group.
A colorless crystalline solid. Toxic by ingestion and is strongly irritating to skin and eyes. 1,6-Diisocyanatohexane is used to make nylon.
Air & Water Reactions
Contact with moisture or temperatures over 399°F may cause polymerization. Soluble in water.
1,6-Diisocyanatohexane reacts with water. Base-catalyzed reactions of 1,6-Diisocyanatohexane with alcohols may be explosively violent in the absence of diluting solvents. 1,6-Diisocyanatohexane is incompatible with strong bases, amines, acids and strong oxidizers. 1,6-Diisocyanatohexane is also incompatible with metal compounds and surface active materials. .
HDI is moderately toxic by inhalation. Inhumans the acute toxic symptoms could bewheezing, dyspnea, sweating, coughing, dif-ficulty in breathing, and insomnia. In addition, this compound can produce irritationof the skin, eyes, nose, and respiratory tract.Chronic exposure may cause obstruction ofairways and asthma.
The lethal concentration for rats frominhalation of this compound for 4 hourswas 60 mg/m3. The oral toxicity of thiscompound was found to be low in testanimals. The toxicity order was much higherwhen given intravenously.
LD50 value, oral (mice): 350 mg/kg
LD50 value, intravenous (mice): 5.6 mg/kg
There is no report of any carcinogenic orteratogenic study for this compound.
Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
This diisocyanate compound is used in the manufac ture of various polyurethane products: elastic and rigid foams, paints, lacquers, adhesives, binding agents, synthetics rubbers, and elastomer fibers.
Poison by inhalation and intravenous routes. Moderately toxic by ingestion and skin contact. Potentially explosive reaction with alcohols + base. When heated to decomposition it emits toxic fumes of NOx. See also CYANATES.
Used to make other chemicals, coat ings, and polyurethane. It is also used as a hardener in automobile and airplane paints.
UN2281 Hexamethylene diisocyanate, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
May form explosive mixture with air. Isocyanates are highly flammable and reactive with many compounds, even with themselves. Incompatible with oxi dizers (chlorates, nitrates, peroxides, permanganates, per chlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Reaction with moist air, water or alcohols may form amines and insoluble polyureas and react exothermically, releasing toxic, corrosive or flamma ble gases, including carbon dioxide; and, at the same time, may generate a violent release of heat increasing the con centration of fumes in the air. Incompatible with amines, aldehydes, alkali metals, ammonia, carboxylic acids, capro lactum, alkaline materials, glycols, ketones, mercaptans, hydrides, organotin catalysts, phenols, strong acids, strong bases, strong reducing agents such as hydrides, urethanes, ureas. Elevated temperatures or contact with acids, bases, tertiary amines, and acyl-chlorides may cause explosive polymerization. Attacks some plastics, rubber and coatings. Contact with metals may evolve flammable hydrogen gas. May accumulate static electrical charges, and may cause ignition of its vapors. Temperatures above 200℃ can cause polymerization. Attacks copper.
Disposal is by chemical incineration of HDIsolution in a combustible solvent.
Hexamethylene Diisocyanate Preparation Products And Raw materials
- 010-82848833- ;010-82848833-
- 400-610-6006; 021-67582000
- 021-67121386 / 800-988-0390
- ISOCYANIC ACID
- Hexanedioic acid, polymer with 1,6-diisocyanatohexane, 2,2-dimethyl-1,3-propanediol and 1,2-ethanediol
- 1-Naphthyl isocyanate
- Fluorescein isothiocyanate
- METHYLISOCYANATE 1 X 500MG NEAT
- ISOTHIOCYANATE, POLYMER-BOUND, 200-400
- Hexamethylene Diisocyanate
- TRIMETHYL-1 6-DIISOCYANATOHEXANE 99
- TRIMETHYL-1,6-HEXAMETHYLENE DIISOCYANATE
- 2,2,4-trimethylhexa-1,6-diyl diisocyanate
- Propyl isocyanate
- cyanic acid