SPIROXATRINE Chemical Properties

Melting point:

215.8-218.0 °C

Boiling point:

602.8±55.0 °C(Predicted)

Density 

1.32±0.1 g/cm3(Predicted)

storage temp. 

Store at RT

solubility 

0.1 M HCl: moderately soluble

form 

powder

pka

15.03±0.20(Predicted)

color 

white

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

SPIROXATRINE Usage And Synthesis

Uses

Spiroxatrine (R 5188) is a SR-1A antagonist.

Definition

ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines.

Biological Activity

5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.

SPIROXATRINE(1054-88-2)Related Product Information

• 2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE
• Piperoxan
• 4-(DIETHYLAMINO)BUTYLAMINE
• 2-Isopropoxyphenol
• 3-PIPERIDINO-1,2-PROPANEDIOL
• N-(1-METHYLPIPERIDIN-4-YL)ANILINE
• SPIROXATRINE
• Hexahydroisonicotinamide
• (1-Methyl-4-piperidinyl)methanamine
• 2-(2-Methoxyphenoxy)ethylamine
• 1,3-Propanediamine,N3,N3-dimethyl-1-phenyl-
• N-(2-Hydroxyethyl)-1,4-butanediamine
• 1-METHYLPIPERIDINE-4-CARBALDEHYDE
• 1,4-Benzodioxan
• 2-methyl-1,4-diaminobutane
• 1,4-BENZODIOXAN-2-METHYLAMINE, N-METHYL-
• CHEMBRDG-BB 4009655
• 1-[1-(2-METHOXYETHYL)PIPERIDIN-4-YL]METHANAMINE