Basic information Safety Supplier Related

(-)-SCOPOLAMINE

Basic information Safety Supplier Related

(-)-SCOPOLAMINE Basic information

Product Name:
(-)-SCOPOLAMINE
Synonyms:
  • HYOSCINE
  • Azatricyclo [3.3.1.02,4] non-7-yl ester
  • Benzeneaceticacid,α-(hydroxymethyl)-,(1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-
  • (1alpha,2beta,4beta,5alpha,7beta)-alpha-(Hydroxymethyl)-benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo[3.3.1.0(2,4)]non-7-yl ester
  • (1R,2R,4S,5R)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 3-hydroxy-2-phenylpropanoate
  • Benzeneacetic acid, α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester
  • Atropine Impurity 17
  • (-)-SCOPOLAMINE
CAS:
138-12-5
MF:
C17H21NO4
MW:
303.35
Mol File:
138-12-5.mol
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(-)-SCOPOLAMINE Chemical Properties

Boiling point:
460.3±45.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
pka
14.11±0.10(Predicted)
CAS DataBase Reference
138-12-5(CAS DataBase Reference)
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(-)-SCOPOLAMINE Usage And Synthesis

Uses

(±)-Scopolamine (Atroscine) is the racemic modification of Scopolamine. (±)-Scopolamine inhibits α-adrenergic receptor activity. (±)-Scopolamine has Ki values of 33 μM and 7.25 nM for α1-adrenerg receptor and muscarinic cholinergic receptor, respectively[1].

References

[1] Cantor EH, et al. Structure-activity requirements for hypotension and alpha-adrenergic receptor blockade by analogues of atropine. Eur J Pharmacol. 1983 May 20;90(1):75-83. DOI:10.1016/0014-2999(83)90215-7

(-)-SCOPOLAMINESupplier

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