Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  7-Fluoroindole

7-Fluoroindole

Basic information Safety Supplier Related

7-Fluoroindole Basic information

Product Name:
7-Fluoroindole
Synonyms:
  • BUTTPARK 24\07-35
  • 7-FLUOROINDOLE
  • 7-FLUORO-1H-INDOLE
  • 1H-Indole, 7-fluoro-
  • 7-ETHOXYINDOLE
  • 7-Fluoroindoline-2-one
  • 7-Fluoroindole,97%
  • 6-(2-(diMethylaMino)vinyl)-5-nitropyriMidine-2,4(1H,3H)-dione
CAS:
387-44-0
MF:
C8H6FN
MW:
135.14
EINECS:
640-248-2
Product Categories:
  • Building Blocks
  • C7 to C10
  • C7 to C9
  • Chemical Synthesis
  • Fluorinated Building Blocks
  • Halogenated Heterocycles
  • Indoles
  • Simple Indoles
  • Fluorinated heterocyclic series
  • Heterocyclic Building Blocks
  • Heterocyclic Fluorinated Building Blocks
  • New Products for Chemical Synthesis
  • Other Fluorinated Heterocycles
  • Fluorine series
  • Indoles and derivatives
  • Indole
Mol File:
387-44-0.mol
More
Less

7-Fluoroindole Chemical Properties

Melting point:
61 °C
Boiling point:
258.0±13.0 °C(Predicted)
Density 
1.273±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in methanol. (almost transparency)
pka
15.55±0.30(Predicted)
BRN 
114740
InChIKey
XONKJZDHGCMRRF-UHFFFAOYSA-N
CAS DataBase Reference
387-44-0(CAS DataBase Reference)
More
Less

Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
26-36-39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29339900

MSDS

  • Language:English Provider:ALFA
More
Less

7-Fluoroindole Usage And Synthesis

Chemical Properties

Brown solid

Uses

7-Fluoroindole is a reagent used in chemical synthesis. It has been used to synthesize antiviral compounds against Pseudomonas aeruginosa and Staphylococcus aureus along with creation of immunomodulators.
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Antimicrobial activity

7-fluoroindole (7FI) was identified as a compound that inhibits biofilm formation and blood hemolysis without inhibiting the growth of planktonic P. aeruginosa cells. Moreover, 7FI markedly reduced the production of quorum-sensing (QS)-regulated virulence factors 2-heptyl-3-hydroxy-4(1H)-quinolone, pyocyanin, rhamnolipid, two siderophores, pyoverdine and pyochelin. 7FI clearly suppressed swarming motility, protease activity and the production of a polymeric matrix in P. aeruginosa. However, unlike natural indole compounds, synthetic 7FI did not increase antibiotic resistance. Therefore, 7FI is a potential candidate for use in an antivirulence approach against persistent P. aeruginosa infection.

7-Fluoroindole Preparation Products And Raw materials

Raw materials

7-FluoroindoleSupplier

Win-Win Chemical CO., Limited Gold
Tel
057764498589
Email
sales@win-winchemical.com
Suzhou QIHANG Biotechnology Co., Ltd Gold
Tel
18662190603
Email
437347250@qq.com
Shanghai HongMin Pharmaceutical Co., Ltd.
Tel
13651987816
Email
hongminpharm@163.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 13770978108
Email
sales@pharmablock.com