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Gestodene

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Gestodene Basic information

Product Name:
Gestodene
Synonyms:
  • (8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one
  • 17-alpha-Ethynyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one
  • 18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha)
  • (17R)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
  • 15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-6,12-dien-5-one
  • Gestodene Methyl analogue: 17alpha-(1-Propyn-1-yl)-17a-hydroxy-18-Methyl-4,15-estradien-3-one
  • (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • (8R,9S,10R,13S,14S,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,7,8,10,11,12,13,17-octahydro-2H-cyclopenta[a]phenanthren-3(6H,9H,14H)-one
CAS:
60282-87-3
MF:
C21H26O2
MW:
310.43
EINECS:
262-145-8
Product Categories:
  • Steroid and Hormone
  • Hormone Drugs
  • Miscellaneous Biochemicals
  • Hormone
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
Mol File:
60282-87-3.mol
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Gestodene Chemical Properties

Melting point:
190-192°C
Boiling point:
462.7±45.0 °C(Predicted)
Density 
1.15±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO: >20mg/mL
form 
powder
pka
12.16±0.40(Predicted)
color 
white to off-white
optical activity
[α]/D -175 to -195° (DCM)
λmax
240nm(MeOH)(lit.)
Merck 
14,4413
InChIKey
SIGSPDASOTUPFS-XUDSTZEESA-N
CAS DataBase Reference
60282-87-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
62
Safety Statements 
36/37-24/25
WGK Germany 
3
RTECS 
JF7956000
HS Code 
29144000
Hazardous Substances Data
60282-87-3(Hazardous Substances Data)
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Gestodene Usage And Synthesis

Description

Gestodene is a progestogen, recently launched in combination with ethinyl estradiol as an oral contraceptive.Gestodene is a steroid. It has a role as an estrogen.Gestodene, one of three new gonane progestins, is the most potent on a per weight basis in regard to progestational effects and has little or no estrogenic effect. In in vivo animal studies, gestodene also has less androgenic activity compared with progestins found in older combination oral contraceptive formulations.

Chemical Properties

White Crystalline Solid

Originator

Schering AG (W. Germany)

Uses

Gestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive.

Uses

Orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.

Uses

Estrogens and progestins are female hormones. They are produced by the body and are necessary for the normal sexual development of the female and for the regulation of the menstrual cycle during the childbearing years. Gestodene is a progestogen hormonal

Definition

ChEBI: Gestodene is a steroid. It has a role as an estrogen.

brand name

Femodene

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