1,1,1-Trimethoxy-2-chloroethane Chemical Properties

Boiling point:

138 °C (lit.)

Density 

1.147 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.425(lit.)

Flash point:

109 °F

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Oil

color 

Colourless

InChIKey

NPEIUNVTLXEOLT-UHFFFAOYSA-N

CAS DataBase Reference

74974-54-2(CAS DataBase Reference)

NIST Chemistry Reference

1,1,1-Trimethoxy-2-chloroethane(74974-54-2)

Safety Information

Hazard Codes 

T

Risk Statements 

10

Safety Statements 

16-45

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

1,1,1-Trimethoxy-2-chloroethane Usage And Synthesis

Uses

2-Chloro-1,1,1-trimethoxyethane may be used for the synthesis of chlorotriazolinone, an NK₁ antagonist and 2-chloromethyl-7-[3-(trifluoromethyl)pyridin-2-yl]-3H-quinazolin-4-one.

General Description

2-Chloro-1,1,1-trimethoxyethane is a chloromethyl heterocyclic compound. It participates in the synthesis of 2-phenyl-1,3,4-oxadiazole derivatives.

1,1,1-Trimethoxy-2-chloroethane (74974-54-2)Related Product Information

• Trimethyl borate
• Ethyl malonyl chloride
• Fosaprepitant Impurity 5
• 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one
• (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one
• Aprepitant
• (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
• Benzyl dihydrogen phosphate
• (2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine
• 4-Methoxybenzylchloride
• CHLOROETHANE
• 1,1,2,2-Tetrachloroethane
• 1-Chloro-1,1-difluoroethane
• Difluorochloromethane
• Trimethyl orthoacetate
• Chloroacetaldehyde dimethyl acetal
• 2-Chloro-1,1,1-triethoxyethane
• ORTHODICHLOROACETIC ACID TRIETHYL ESTER