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5-Methylisatin

Basic information Safety Supplier Related

5-Methylisatin Basic information

Product Name:
5-Methylisatin
Synonyms:
  • AURORA 1898
  • BUTTPARK 34\07-89
  • IFLAB-BB F0266-0774
  • 5-methylindole-2,3(1H)-dione
  • 5-METHYL-1H-INDOLE-2,3-DIONE
  • 5-METHYLISATIN
  • 5-METHYLINDOLE-2,3-DIONE
  • AKOS BBS-00000995
CAS:
608-05-9
MF:
C9H7NO2
MW:
161.16
EINECS:
210-152-1
Product Categories:
  • Building Blocks
  • C7 to C9
  • Indane/Indanone and Derivatives
  • Indoles
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Simple Indoles
Mol File:
608-05-9.mol
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5-Methylisatin Chemical Properties

Melting point:
180 °C (dec.) (lit.)
Density 
1.301±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
methanol: soluble25mg/mL, clear to slightly hazy, orange to red
pka
10.42±0.20(Predicted)
form 
crystalline
color 
orange
BRN 
123738
CAS DataBase Reference
608-05-9(CAS DataBase Reference)
NIST Chemistry Reference
5-Methyl-2,3-indolinedione(608-05-9)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
RTECS 
NL7939300
HazardClass 
IRRITANT
HS Code 
29337900

MSDS

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5-Methylisatin Usage And Synthesis

Chemical Properties

Red to brown powder or crystals

Uses

Reactant for preparation of:

  • Antimycobacterial agents
  • Promoters of central nervous system (CNS) depression in mice
  • Inhibitors of TAK1 kinase
  • Anti-human immunodeficiency virus (HIV) agent
  • Potent herpes simplex virus (HSV) inhibitors
  • Antimicrobial agents
  • IKKβ inhibitors
  • Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection
  • Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors
  • Antibacterial and anticancer agents

Uses

Reactant for preparation of:• ;Antimycobacterial agents1• ;Promoters of central nervous system (CNS) depression in mice2• ;Inhibitors of TAK1 kinase3• ;Anti-human immunodeficiency virus (HIV) agent4• ;Potent herpes simplex virus (HSV) inhibitors5• ;Antimicrobial agents6• ;IKKβ inhibitors7• ;Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection8• ;Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors9• ;Antibacterial and anticancer agents

General Description

5-Methylisatin is an inhibitor of atrial natriuretic peptide (ANP) receptor coupled with guanylyl cyclase (GC).

5-MethylisatinSupplier

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