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1-(2,6-Dichlorophenyl)indolin-2-one

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1-(2,6-Dichlorophenyl)indolin-2-one Basic information

Product Name:
1-(2,6-Dichlorophenyl)indolin-2-one
Synonyms:
  • Diclofenac PotassiumⅠ:1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one
  • Diclofenac Sodium ImpurityⅠ: 1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one
  • Indolinone (Diclofenac Amide, Diclofenac Lactam)
  • DICLOFENAC RELATED COMPOUND A (50 MG) (N-(2,6-DICHLOROPHENYL)INDOLIN-2-ONE)
  • 1-(2,6-Dichlorophenyl)-2,3-dihydro-1H-indole-2-one
  • Diclofenac Amide
  • 6-Dichlorophenyl)-2-indolinone
  • N-(2,6-Dichlorophenyl)-Indolin-(2)-One
CAS:
15362-40-0
MF:
C14H9Cl2NO
MW:
278.13
EINECS:
239-399-3
Product Categories:
  • Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Aromatics
  • Heterocycles
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
15362-40-0.mol
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1-(2,6-Dichlorophenyl)indolin-2-one Chemical Properties

Melting point:
115-119°C
Boiling point:
488.6±45.0 °C(Predicted)
Density 
1.432±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
-4.85±0.20(Predicted)
color 
Off-White to Light Brown
BRN 
1538309
Stability:
Stability
CAS DataBase Reference
15362-40-0(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
NM3259200
HS Code 
29337900
Toxicity
mouse,LD50,unreported,1200mg/kg (1200mg/kg),Pharmaceutical Chemistry Journal Vol. 21, Pg. 275, 1987.
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1-(2,6-Dichlorophenyl)indolin-2-one Usage And Synthesis

Chemical Properties

Off-White to Light Brown Solid

Uses

1-(2,6-Dichlorophenyl)indolin-2-one is a potential prodrug of Diclofenac and possible impurity during its commercial synthesis. It is Aceclofenac EP Impurity I and Diclofenac Impurity A.

1-(2,6-Dichlorophenyl)indolin-2-oneSupplier

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