ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Cytoskeletal Signaling > HSP e.g. HSP90 inhibitors > 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Basic information
- Product Name:
- 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
- Synonyms:
-
- 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
- 8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylaMino)propyl)-9H-purin-6-aMine
- PU-H71 Trifluoroacetic Acid
- 9H-Purine-9-propanamine, 6-amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-
- NSC 750424
- 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine PU-H71 Trifluoroacetic Acid
- PU-H71, >=98%
- 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine
- CAS:
- 873436-91-0
- MF:
- C18H21IN6O2S
- MW:
- 512.37
- Product Categories:
-
- API
- Inhibitors
- Mol File:
- 873436-91-0.mol
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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Chemical Properties
- Melting point:
- >194oC (dec.)
- Boiling point:
- 650.6±65.0 °C(Predicted)
- Density
- 1.84
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 10.16±0.29(Predicted)
- form
- Solid
- color
- Off-White to Pale Beige
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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Usage And Synthesis
Uses
Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamineSupplier
Shanghai Changyu Medical Technology Co. Ltd. Gold
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- +86-13301875428
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Shanghai Boyle Chemical Co., Ltd.
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J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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Chembest Research Laboratories Limited
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Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine(873436-91-0)Related Product Information
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