6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine

Product Name: 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
CAS No.: 873436-91-0
Chemical Name: 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
Synonyms: CS-105;PU-H 71;NSC 750424;PU-H71 XHBr;PU-H71, >=98%;Zelavespib (PU-H71);PU-H71 Trifluoroacetic Acid;9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine;8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine;8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylaMino)propyl)-9H-purin-6-aMine
CBNumber: CB42554288
Molecular Formula: C18H21IN6O2S
Formula Weight: 512.37
MOL File: 873436-91-0.mol

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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Property

Melting point:: >194oC (dec.)
Boiling point:: 650.6±65.0 °C(Predicted)
Density: 1.84
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 10.16±0.29(Predicted)
form: Solid
color: Off-White to Pale Beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 3104
Product name: PUH71
Purity: ≥98%(HPLC)
Packaging: 10
Price: $212
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FP65141
Product name: PU-H71
Packaging: 10mg
Price: $85
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 48446
Product name: PU-H71TrifluoroaceticAcid
Packaging: 100mg
Price: $2200
Updated: 2021/12/16

Crysdot

Product number: CD31000467
Product name: PU-H71
Purity: 98+%
Packaging: 10mg
Price: $55
Updated: 2021/12/16

Crysdot

Product number: CD31000467
Product name: PU-H71
Purity: 98+%
Packaging: 50mg
Price: $252
Updated: 2021/12/16

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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Chemical Properties,Usage,Production

Uses

Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Suppliers

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Shanghai Changyu Medical Technology Co. Ltd.

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MedChemexpress LLC

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Shanghai Witofly Chemical Co.,Ltd

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873436-91-0, 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamineRelated Search:

4SC-202 CEP-32496 N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine PURVALANOL A Testolactone GDC-0077 AGI6780 CC0651 IDO-IN-7 UNC 0631 XL 228 N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea Alectinib BIIB-021 Onalespib 17-AAG Ganetespib BEZ235 (NVP-BEZ235, Dactolisib)

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine

8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylaMino)propyl)-9H-purin-6-aMine

PU-H71 Trifluoroacetic Acid

9H-Purine-9-propanamine, 6-amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-

NSC 750424

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine PU-H71 Trifluoroacetic Acid

PU-H71, >=98%

8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine

9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine

PU-H 71

CS-105

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine USP/EP/BP

Zelavespib (PU-H71)

PU-H71 XHBr

873436-91-0

C18H21IN6O2S

API

Inhibitors